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注意缺陷多动障碍(ADHD)患儿及青少年的事故易发性与药物治疗的影响

Accident Proneness in Children and Adolescents Affected by ADHD and the Impact of Medication.

作者信息

Lange Hannah, Buse Judith, Bender Stephan, Siegert Joachim, Knopf Hildtraud, Roessner Veit

机构信息

University of Dresden Medical School, Germany

University of Dresden Medical School, Germany.

出版信息

J Atten Disord. 2016 Jun;20(6):501-9. doi: 10.1177/1087054713518237. Epub 2014 Jan 27.

Abstract

OBJECTIVE

This study aims to ascertain once and for all whether children and adolescents affected by ADHD show a higher risk for accidents, as well as investigating a possible association between the administration of ADHD-specific medication and the occurrence of accidents.

METHOD

Two exceptionally large sets of data were implemented in this analysis. Participants included children and adolescents representative of the entire German population. Data for Survey 1 was collected through extensive administration of questionnaires. Data for Survey 2 stemmed from the records of a leading German health insurance company. In terms of statistical analysis, chi-square tests as well as logistic regression analyses were applied and odds ratios (ORs) were determined.

RESULTS

Innovative results are presented showing a significantly higher likelihood for ADHD-affected youngsters to be involved in accidents compared with their nonaffected counterparts (Survey 1: OR = 1.60; Survey 2: OR = 1.89) but lacking an overall significant influence of medication regarding the occurrence of accidents (Survey 1: OR = 1.28; Survey 2: OR = 0.97). Frequency of accidents could be predicted by ADHD, gender, and age in both samples. Medication intake served as a weak predictor only in Survey 2.

CONCLUSION

It has been determined in two representative and independent German samples that youngsters with ADHD are at a significantly higher risk of being involved in accidents. In the future, this should always be considered when setting up a treatment plan to ensure a safer and healthier coming of age without relying solely on specific effects of medication. (J. of Att. Dis. 2016; 20(6) 501-509).

摘要

目的

本研究旨在一劳永逸地确定受注意力缺陷多动障碍(ADHD)影响的儿童和青少年是否有更高的事故风险,并调查ADHD特异性药物治疗与事故发生之间可能存在的关联。

方法

本分析采用了两组特别大的数据集。参与者包括代表整个德国人口的儿童和青少年。调查1的数据通过广泛发放问卷收集。调查2的数据来自德国一家领先的健康保险公司的记录。在统计分析方面,应用了卡方检验和逻辑回归分析,并确定了优势比(OR)。

结果

呈现的创新性结果表明,与未受影响的同龄人相比,受ADHD影响的青少年发生事故的可能性显著更高(调查1:OR = 1.60;调查2:OR = 1.89),但药物治疗对事故发生总体上没有显著影响(调查1:OR = 1.28;调查2:OR = 0.97)。在两个样本中,ADHD、性别和年龄都可以预测事故发生频率。仅在调查2中,药物摄入是一个较弱的预测因素。

结论

在两个具有代表性且相互独立的德国样本中已确定,患有ADHD的青少年发生事故的风险显著更高。未来,在制定治疗计划时应始终考虑到这一点,以确保在不单纯依赖药物特定效果的情况下,实现更安全、更健康的成长。(《注意缺陷障碍杂志》2016年;20(6) 501 - 509)

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