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恶性梅毒作为HIV感染的首发表现。

Malignant syphilis as the first manifestation of HIV infection.

作者信息

Rallis Efstathios, Paparizos Vasileios

机构信息

Department of Dermatology, Veterans Administration Hospital (NIMTS);

Sexually Transmitted Infections Unit, A. Sygros Hospital, Athens, Greece.

出版信息

Infect Dis Rep. 2012 Feb 23;4(1):e15. doi: 10.4081/idr.2012.e15. eCollection 2012 Jan 2.

DOI:10.4081/idr.2012.e15
PMID:24470922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3892643/
Abstract

Malignant syphilis is a rare and severe variant of secondary syphilis. It is clinically characterized by large papular, nodular and ulcerative lesions affecting the trunk and the extremities and covered with thick crust. We present a case of 52-year-old homosexual male who developed malignant syphilis and this was the first clinical manifestation of HIV infection. The patient was treated successfully with intravenous aqueous crystalline penicillin G. Physicians should recognize malignant syphilis and consider it in all HIV-infected individuals with ulceronodular skin lesions.

摘要

恶性梅毒是二期梅毒中一种罕见且严重的变异型。其临床特征为躯干和四肢出现大丘疹、结节及溃疡性损害,并覆盖有厚痂。我们报告一例52岁的同性恋男性,其患恶性梅毒,这是其HIV感染的首发临床表现。该患者经静脉注射水溶性结晶青霉素G成功治愈。医生应认识到恶性梅毒,并在所有患有溃疡结节性皮肤损害的HIV感染者中考虑该病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/43e76b3499a9/idr-2012-1-e15-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/67af172aebb5/idr-2012-1-e15-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/86f0a8c78154/idr-2012-1-e15-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/866c0a12ad83/idr-2012-1-e15-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/89f54ce18367/idr-2012-1-e15-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/43e76b3499a9/idr-2012-1-e15-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/67af172aebb5/idr-2012-1-e15-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/86f0a8c78154/idr-2012-1-e15-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/866c0a12ad83/idr-2012-1-e15-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/89f54ce18367/idr-2012-1-e15-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d546/3892643/43e76b3499a9/idr-2012-1-e15-g005.jpg

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本文引用的文献

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Malignant syphilis with ocular involvement in an HIV-infected patient.一名感染HIV的患者发生伴有眼部受累的恶性梅毒。
Int J STD AIDS. 2011 May;22(5):298-300. doi: 10.1258/ijsa.2010.010389.
2
Lues maligna in early HIV infection case report and review of the literature.早期HIV感染中的恶性梅毒:病例报告及文献综述
Sex Transm Dis. 2009 Aug;36(8):512-4. doi: 10.1097/OLQ.0b013e3181a2a946.
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Lues maligna.恶性梅毒
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Malignant syphilis in HIV-infected patients.
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