Lutf Abdo, Poil Abdul R, Hammoudeh Mohammed
Rheumatology Division, Department of Medicine, Hamad General Hospital, Doha, Qatar.
Int J Rheum Dis. 2014 Jan;17(1):63-5. doi: 10.1111/1756-185X.12135. Epub 2013 Jul 16.
To describe the clinical characteristics, serologic, radiological and clinical disease activity, and modality of therapy in patients with rheumatoid arthritis (RA) at tertiary outpatient care in Qatar.
The study design was cross-sectional where 100 consecutive cases who met 1987 American College of Rheumatology criteria for diagnosis of RA were enrolled in this study. Demographic data (sex, nationality and age) numbers of swollen and tender joints, X-rays and current medications were collected during outpatients visits to Hamad General Hospital. Disease Activity Score of 28 joints (DAS28) and Health Assessment Questionnaires (HAQ) scores were calculated. All patients with RA who were seen as rheumatology outpatients were invited to participate in the study.
One hundred patients were seen and examined during their follow-up at the outpatient clinic; data were collected and analyzed. Females represented 67% of all patients, 6% had more than six swollen joints, 9% had more than six tender joints. DAS28 and erythrocyte sedimentation rate (DAS28) calculation revealed 49% of patients were in remission (DAS28 < 2.6), 15% had low disease activity (DAS28 2.6-3.2) and 36% had DAS28 > 3.2.Mean HAQ score was 1.02. Rheumatoid factor (RF) was positive in 63%, while anti-cyclic citrullinated protein antibody (anti-CCP) was positive in 71%, and 49% were positive for both. Radiography of hands and feet during the previous year was done in 65% of patients: 11% of them had erosions. Sixty-six percent were on one synthetic disease-modifying anti-rheumatic drug (DMARD) and 27% where on more than one synthetic DMARD and 7% where on no DMRD. Glucocorticoids were used in 51% and 29% were on biologics.
Sixty-four percent of rheumatoid arthritis patients in Qatar were in remission or had low disease activity while the remaining 36% had active disease and among these patients 29% were on biologics.
描述卡塔尔三级门诊护理中类风湿关节炎（RA）患者的临床特征、血清学、放射学及临床疾病活动度和治疗方式。
本研究为横断面研究，纳入100例符合1987年美国风湿病学会RA诊断标准的连续病例。在患者到哈马德总医院门诊就诊期间，收集人口统计学数据（性别、国籍和年龄）、肿胀和压痛关节数、X线检查结果及当前用药情况。计算28个关节的疾病活动评分（DAS28）和健康评估问卷（HAQ）评分。所有在风湿病门诊就诊的RA患者均受邀参与本研究。
100例患者在门诊随访期间接受了检查；收集并分析了数据。女性占所有患者的67%，6%的患者有超过6个肿胀关节，9%的患者有超过6个压痛关节。DAS28和红细胞沉降率（DAS28）计算结果显示，49%的患者病情缓解（DAS28<2.6），15%的患者疾病活动度低（DAS28 2.6 - 3.2），36%的患者DAS28>3.2。HAQ评分均值为1.02。类风湿因子（RF）阳性率为63%，抗环瓜氨酸肽抗体（抗CCP）阳性率为71%，49%的患者两者均为阳性。65%的患者在前一年进行了手足部X线检查：其中11%有骨质侵蚀。66%的患者使用一种合成改善病情抗风湿药（DMARD），27%的患者使用一种以上合成DMARD，7%的患者未使用DMARD。51%的患者使用糖皮质激素，29%的患者使用生物制剂。
卡塔尔64%的类风湿关节炎患者病情缓解或疾病活动度低，其余36%的患者疾病活动，其中29%的患者使用生物制剂。
