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[职业与环境卫生大学108例连续原发性肝恶性肿瘤的临床病理研究]

[A clinicopathological study of 108 consecutive primary hepatic malignancies in the University of Occupational and Environmental Health].

作者信息

Haratake J, Horie A, Taoka Y, Okuno F, Takeda S, Sato H

机构信息

Dept. of Pathol. Oncol., School of Med., Univ. OEH.

出版信息

Gan No Rinsho. 1987 Oct;33(13):1689-93.

PMID:2447304
Abstract

At our University, the rate of hepatic malignancies among the total number of those autopsied was shown to be higher than the mean rate of Japan. The 108 cases investigated included 92 hepatocellular carcinomas (HCCs), 10 cholangiocellular carcinomas (CCCs), 4 cases of combined HCC and CCC, one undifferentiated carcinoma, and one angiosarcoma. The positive rate of serum HBsAg among the HCCs in our series was almost equal to the mean rate of Japan. Twenty-eight HBsAg positive and 64 negative HCCs were clinicopathologically compared. The mean age at death was ten years younger for the positive cases than in the negative ones (p less than 0.05). However, there was no significant difference between both groups in any other biologic or pathologic feature, except for a few minor matters. We describe herein the summary of our cases with reference to a comparison study between HBsAg positive and negative HCC cases.

摘要

在我校,尸检总数中肝脏恶性肿瘤的发生率高于日本的平均发生率。所调查的108例病例包括92例肝细胞癌(HCC)、10例胆管细胞癌(CCC)、4例HCC合并CCC、1例未分化癌和1例血管肉瘤。本系列HCC患者血清HBsAg阳性率几乎与日本的平均水平相当。对28例HBsAg阳性和64例阴性HCC进行了临床病理比较。阳性病例的平均死亡年龄比阴性病例小10岁(p<0.05)。然而,除了一些小问题外,两组在任何其他生物学或病理学特征上均无显著差异。在此,我们参照HBsAg阳性和阴性HCC病例的比较研究描述我们的病例总结。

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