Ilhan Ozgur, Agacayak Kamil Serkan, Gulsun Belgin, Koparal Mahmut, Gunes Nedim
Department of Oral and Maxillofacial Surgery, Oral and Dental Health Center, Mersin, Turkey.
Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Dicle, Diyarbakır, Turkey.
Med Sci Monit. 2014 Jan 29;20:147-52. doi: 10.12659/MSM.890239.
The aim of the present study was to compare the effects of preemptive intravenous tenoxicam and methylprednisolone administrations on extraction of impacted third molars.
This was a placebo-controlled, randomized, double-blind, clinical trial. A total of 60 adult patients ages 18-40 years with the complaints of impacted third molar teeth were included in the study.
The postoperative swelling ratios (p<0.05) and pain scores (p<0.05) were significantly better in both study groups than in the control group and there was no statistically significant difference between methylprednisolone and tenoxicam groups with regards to the edema and pain relief.
Preoperative administration of 80 mg methylprednisolone achieves better control of trismus than tenoxicam without any significant differences in edema and pain control in impacted third molar teeth extraction.
本研究的目的是比较预防性静脉注射替诺昔康和甲泼尼龙对拔除阻生第三磨牙的影响。
这是一项安慰剂对照、随机、双盲临床试验。共有60名年龄在18 - 40岁、主诉为阻生第三磨牙的成年患者纳入研究。
两个研究组的术后肿胀率（p<0.05）和疼痛评分（p<0.05）均显著优于对照组，且甲泼尼龙组和替诺昔康组在水肿和疼痛缓解方面无统计学显著差异。
在拔除阻生第三磨牙时，术前给予80mg甲泼尼龙比替诺昔康能更好地控制牙关紧闭，在水肿和疼痛控制方面无显著差异。
