Departamento de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia, Hospital Heliópolis, São PauloSP.
Departamento de Saúde, Hospital Heliópolis, São Paulo.
Braz J Otorhinolaryngol. 2013 Nov-Dec;79(6):734-7. doi: 10.5935/1808-8694.20130134.
The presence of metastatic nodes is a survival-limiting factor for patients with mouth tumors.
To evaluate the causes of treatment failure in carcinomas of the tongue and floor of the mouth due to staging.
This study included 365 patients with squamous cell carcinoma of the mouth treated from 1978 to 2007; 48 were staged as T1, 156 as T2, 98 as T3, and 63 as T4, of which 193 were pNo and 172 pN+.
Among the pN+ cases, 17/46 (36.9%) of the patients not treated with radiation therapy had relapsing tumors, against 46/126 (36.5 %) of the patients who underwent radiation therapy. Success rates in the group of subjects submitted to salvage procedures were 16/51 (31.3%) for pN0 patients and 3/77 (3.9%) for pN+ patients.
Salvage procedure success and survival rates are lower for pN+ patients; pN+ individuals also have more relapsing local disease.
转移淋巴结的存在是口腔肿瘤患者生存的限制因素。
评估因分期导致的舌和口底癌治疗失败的原因。
本研究纳入了 1978 年至 2007 年间接受治疗的 365 例口腔鳞状细胞癌患者；48 例 T1 期，156 例 T2 期，98 例 T3 期，63 例 T4 期，其中 193 例 pNo，172 例 pN+。
在未接受放疗的 pN+病例中，有 17/46（36.9%）例肿瘤复发，而接受放疗的病例中，有 46/126（36.5%）例肿瘤复发。在接受挽救性手术的患者中，pN0 患者的成功率为 16/51（31.3%），pN+患者的成功率为 3/77（3.9%）。
pN+患者的挽救性手术成功率和生存率较低；pN+患者局部复发疾病的比例也更高。
