肾盂原发性大细胞神经内分泌癌：一例报告

Primary large cell neuroendocrine carcinoma of the renal pelvis: a case report.

作者信息

Palumbo Carlotta, Talso Michele, Dell'Orto Paolo Guido, Cozzi Gabriele, De Lorenzis Elisa, Conti Andrea, Maggioni Marco, Cesare Rocco Bernardo Maria, Maggioni Augusto, Rocco Francesco

机构信息

Department of Urology, University of Milan, IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan - Italy.

出版信息

Urologia. 2014 Jan-Mar;81(1):57-9. doi: 10.5301/urologia.5000033. Epub 2013 Nov 28.

DOI:10.5301/urologia.5000033

PMID:24474544

Abstract

We report a case of primary large cell neuroendocrine carcinoma of the renal pelvis, diagnosed in a 79-year-old man. The abdominal computed tomography showed a solid, vegetant lesion in the left renal pelvis, conditioning marked hydronephrosis. The patient underwent radical nephroureterectomy. The histological examination showed a large cell neuroendocrine carcinoma associated with a high-grade urothelial carcinoma, with local invasion (pT3). Large cell renal neuroendocrine carcinomas are rare tumors with an aggressive course and a bad prognosis. At present, only five cases were reported in literature.

摘要

我们报告了一例肾盂原发性大细胞神经内分泌癌，该病例发生在一名79岁男性身上。腹部计算机断层扫描显示左肾盂有一个实性、赘生性病变，导致明显肾积水。患者接受了根治性肾输尿管切除术。组织学检查显示为大细胞神经内分泌癌，伴有高级别尿路上皮癌，有局部浸润（pT3）。大细胞肾神经内分泌癌是一种罕见肿瘤，病程侵袭性强，预后不良。目前，文献中仅报道了五例。