Shah Chirag, Sheth Navin R, Solanki Bhagirath, Shah Nimisha
Department of Pharmaceutical Sciences, Saurashtra University, Rajkot - 360005.
Dept. of Medicine, B.J. Medical College and Civil Hospital, Asarwa, Ahmedabad -380016.
J Assoc Physicians India. 2013 Mar;61(3):179-84.
The objective of the study to determine the prevalence of Impaired Glucose Tolerance and Impaired Fasting Glucose (both combined termed as Pre Diabetes) in the population of Gujarat.
In year 2007 and 2008, a cross sectional survey was conducted via mode of camps at various urban and rural part of Gujarat. After obtaining an informed consent, comprehensive questionnaire was used to collect the various anthropological details, physical examination and blood collection was performed from around 1700 subjects > or = 20 years of age from the different areas of Gujarat. Chi square test was used for all categorical comparisons. Also multiple logistic regression was used for detailed exploratory analysis.
The crude prevalence of IFG in Gujarati population is around 2.76% and IGT is around 6.12%. But the age adjusted prevalence of IFG is around 2.72% and IGT is around 4.67%. If we extrapolate these to population of Gujarat, it indicates that around 1.3 million people are having impaired fasting glucose and around 2.3 million people have impaired glucose tolerance. The prevalence of IGT found more after age of 40 years. For IFG, there is increase after age of 40 years, but not significant statistically.
High prevalence of IGT validates that there are chances of the pandemic trend in Gujarat, as eventually IGT may get converted into Diabetes in near future. These results need urgent attention to develop a public awareness programme.
本研究旨在确定古吉拉特邦人群中糖耐量受损和空腹血糖受损（两者合称为糖尿病前期）的患病率。
在2007年和2008年，通过在古吉拉特邦城乡各地设立营地的方式进行了一项横断面调查。在获得知情同意后，使用综合问卷收集各种人类学细节，对来自古吉拉特邦不同地区的约1700名年龄≥20岁的受试者进行了体格检查和血液采集。所有分类比较均采用卡方检验。还使用多元逻辑回归进行详细的探索性分析。
古吉拉特邦人群中空腹血糖受损的粗患病率约为2.76%，糖耐量受损约为6.12%。但年龄调整后的空腹血糖受损患病率约为2.72%，糖耐量受损约为4.67%。如果将这些数据推算到古吉拉特邦的人口中，这表明约有130万人空腹血糖受损，约有230万人糖耐量受损。糖耐量受损的患病率在40岁以后更高。对于空腹血糖受损，40岁以后有所增加，但在统计学上不显著。
糖耐量受损的高患病率证实了古吉拉特邦存在大流行趋势的可能性，因为最终糖耐量受损在不久的将来可能会转变为糖尿病。这些结果需要引起紧急关注，以制定公众意识计划。
