From the Department of Diagnostic, Interventional and Pediatric Radiology (E.J.U., C.S., S.E.A., S.E.), Department of Emergency Medicine (H.Z.), and Department of Neurology (M.S.), University Hospital and University of Bern, Inselspital, Bern, Switzerland; Department of Radiology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland (E.J.U., J.H.); and Departments of Clinical Research and Radiology (C.B.) and Institute of Social and Preventive Medicine (A.B.), University of Bern, Bern, Switzerland.
Radiology. 2014 Apr;271(1):172-82. doi: 10.1148/radiol.13120370. Epub 2013 Dec 12.
To provide normal values of the cervical spinal canal and spinal cord dimensions in several planes with respect to spinal level, age, sex, and body height.
This study was approved by the institutional review board; all individuals provided signed informed consent. In a prospective multicenter study, two blinded raters independently examined cervical spine magnetic resonance (MR) images of 140 healthy volunteers who were white. The midsagittal diameters and areas of spinal canal and spinal cord, respectively, were measured at the midvertebral levels of C1, C3, and C6. A multivariate general linear model described the influence of sex, body height, age, and spinal level on the measured values.
There were differences for sex, spinal level, interaction between sex and level, and body height, while age had significant yet limited influence. Normative ranges for the sagittal diameters and areas of spinal canal and spinal cord were defined at C1, C3, and C6 levels for men and women. In addition to a calculation of normative ranges for a specific sex, spinal level, age, and body height data, data for three different height subgroups at 45 years of age were extracted. These results show a range of the spinal canal dimensions at C1 (from 10.7 to 19.7 mm), C3 (from 9.4 to 17.2 mm), and C6 (from 9.2 to 16.8 mm) levels.
The dimensions of the cervical spinal canal and cord in healthy individuals are associated with spinal level, sex, age, and height. Online supplemental material is available for this article.
提供颈椎椎管和脊髓在几个平面上的正常数值，涉及脊柱水平、年龄、性别和身高。
本研究经机构审查委员会批准；所有个体均提供了书面知情同意书。在一项前瞻性多中心研究中，两名盲法评估员独立检查了 140 名白人健康志愿者的颈椎磁共振（MR）图像。分别在 C1、C3 和 C6 的中脊椎水平测量椎管和脊髓的中矢状径和面积。多元线性广义模型描述了性别、身高、年龄和脊柱水平对测量值的影响。
性别、脊柱水平、性别与水平的相互作用以及身高存在差异，而年龄的影响虽显著但有限。为男性和女性在 C1、C3 和 C6 水平定义了椎管矢状径和面积的正常范围。除了为特定性别、脊柱水平、年龄和身高数据计算正常范围外，还提取了 45 岁时三个不同身高亚组的数据。这些结果显示了 C1（10.7-19.7mm）、C3（9.4-17.2mm）和 C6（9.2-16.8mm）水平椎管尺寸的范围。
健康个体的颈椎椎管和脊髓的尺寸与脊柱水平、性别、年龄和身高有关。本文提供了在线补充材料。
