SEIN - Epilepsy Institute in the Netherlands Foundation, Heemstede, The Netherlands, P.O. Box 540, 2130 AM Hoofddorp, The Netherlands.
Int J Neural Syst. 2014 Mar;24(2):1430001. doi: 10.1142/S0129065714300010. Epub 2014 Jan 13.
Transcranial magnetic stimulation (TMS) can be used for safe, noninvasive probing of cortical excitability (CE). We review 50 studies that measured CE in people with epilepsy. Most showed cortical hyperexcitability, which can be corrected with anti-epileptic drug treatment. Several studies showed that decrease of CE after epilepsy surgery is predictive of good seizure outcome. CE is a potential biomarker for epilepsy. Clinical application may include outcome prediction of drug treatment and epilepsy surgery.
经颅磁刺激（TMS）可用于安全、无创地探测皮质兴奋性（CE）。我们综述了 50 项研究，这些研究测量了癫痫患者的 CE。大多数研究显示皮质兴奋性过高，抗癫痫药物治疗可纠正这种现象。一些研究表明，癫痫手术后 CE 的降低与良好的癫痫发作结果相关。CE 是癫痫的一种潜在生物标志物。临床应用可能包括药物治疗和癫痫手术的预后预测。
