Hjertberg R, Belfrage P, Eneroth P
Department of Obstetrics and Gynecology, Karolinska Hospital, Stockholm, Sweden.
Acta Obstet Gynecol Scand. 1987;66(5):437-9. doi: 10.3109/00016348709022050.
A rapid latex agglutination test for alpha-fetoprotein (AFP) was compared with a pH-indicator and patient history in the detection of premature rupture of the amniotic membranes. Of 120 patients examined, 34 had an established rupture of the membranes, and 56 had suspected rupture. Thirty patients had no evidence of membrane rupture. The vaginal content was examined with a pH-indicator. Samples of vaginal content were also obtained to perform the latex agglutination test, and 103 of these samples were analysed by a radio-immunoassay (RIA) technique for AFP. Our results indicate that the latex agglutination test is of doubtful value due to the many inconclusive test results. The sensitivity of the latex test is less than 15%, and the specificity is 80%. Patient history combined with pH-indicator test is far more informative than the latex agglutination test.
在检测胎膜早破方面，将甲胎蛋白（AFP）快速乳胶凝集试验与pH指示剂及患者病史进行了比较。在接受检查的120名患者中，34名患者确诊胎膜破裂，56名患者疑似胎膜破裂。30名患者无胎膜破裂迹象。用pH指示剂检查阴道内容物。还获取阴道内容物样本进行乳胶凝集试验，其中103份样本采用放射免疫分析（RIA）技术检测AFP。我们的结果表明，由于许多检测结果不确定，乳胶凝集试验的价值存疑。乳胶试验的灵敏度低于15%，特异性为80%。患者病史结合pH指示剂试验比乳胶凝集试验提供的信息多得多。
