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痰液中的库施曼螺旋体:支气管腺导管起源的组织化学证据。

Curschmann's spirals in sputum: histochemical evidence of bronchial gland ductal origin.

作者信息

Antonakopoulos G N, Lambrinaki E, Kyrkou K A

机构信息

Department of Histology and Embryology, National University of Athens, Medical School, Greece.

出版信息

Diagn Cytopathol. 1987 Dec;3(4):291-4. doi: 10.1002/dc.2840030406.

DOI:10.1002/dc.2840030406
PMID:2448098
Abstract

Curschmann's spirals from 30 patients suffering from chronic bronchitis were examined histochemically by periodic acid-Schiff (PAS), Alcian blue (AB), PAS-AB, high-iron diamine (HID), and HID-AB stains. Their central core and fibrillar component were found to be rich in neutral mucins and in sulfated and nonsulfated acid mucins, while their outer mantle was rich in neutral and nonsulfated acid mucins only. Curschmann's spirals consist of mucus of high viscosity. Histochemical and morphological evidence suggests that, in addition to their origin in the lumen of smaller bronchi and bronchioles, they are also formed in the ducts of the seromucous bronchial glands.

摘要

对30例慢性支气管炎患者的库施曼螺旋体进行了组织化学检查,采用过碘酸-希夫(PAS)、阿尔辛蓝(AB)、PAS-AB、高铁二胺(HID)和HID-AB染色。发现其核心和纤维成分富含中性粘蛋白以及硫酸化和非硫酸化酸性粘蛋白,而其外层仅富含中性和非硫酸化酸性粘蛋白。库施曼螺旋体由高粘度粘液组成。组织化学和形态学证据表明,它们除了起源于较小支气管和细支气管腔外,还在浆液性支气管腺导管中形成。

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