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成人扁桃体切除术的安全性:5968 例患者的人群水平分析。

Safety of adult tonsillectomy: a population-level analysis of 5968 patients.

机构信息

Department of Surgery, Yale University School of Medicine, New Haven, Connecticut.

Department of Surgery, Duke University School of Medicine, Durham, North Carolina.

出版信息

JAMA Otolaryngol Head Neck Surg. 2014 Mar;140(3):197-202. doi: 10.1001/jamaoto.2013.6215.

Abstract

IMPORTANCE

Tonsillectomy is one of the most commonly performed otolaryngology procedures. The safety of this procedure in adults is based on small case series. To our knowledge, we report the first population-level analysis of the safety of adult tonsillectomies in the United States.

OBJECTIVE

To characterize the mortality, complication, and reoperation rate in adult tonsillectomy.

DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort study of 5968 adult patients who underwent tonsillectomy with records in the database of the American College of Surgeons National Surgical Quality Improvement Program (2005 to 2011).

INTERVENTION

Tonsillectomy.

MAIN OUTCOMES AND MEASURES

Outcomes of interest included mortality, complications, and reoperation in the 30-day postoperative period. Statistical analysis included χ² test, t test, and multivariate logistic regression.

RESULTS

The 30-day mortality rate was 0.03%, the complication rate was 1.2%, and the reoperation rate was 3.2%. Most patients had a primary diagnosis of chronic tonsillitis and/or adenoiditis (82.9%), and the most common complications were pneumonia (27% of all complications), urinary tract infection (27%), and superficial site infections (16%). Patients who underwent reoperation were more likely to be male (54.0% vs 32.4%; P < .001), white (84.8% vs 75.3%; P = .02), or inpatients (24.3% vs 14.3%; P < .001) and to have postoperative complications (5.3% vs 1.1%; P < .001) than those who did not return to the operating room. On multivariate analysis, male sex (odds ratio [OR], 2.30 [95% CI, 1.67-3.15]), inpatient status (OR, 1.52 [95% CI, 1.04-2.22]), and the presence of a postoperative complication (OR, 4.58 [95% CI, 2.11-9.93]) were independent risk factors for reoperation.

CONCLUSIONS AND RELEVANCE

In the United States, adult tonsillectomy is a safe procedure with low rates of mortality and morbidity. The most common posttonsillectomy complications were infectious in etiology, and complications were independently associated with the need for reoperation.

摘要

重要性

扁桃体切除术是耳鼻喉科最常进行的手术之一。该手术在成人中的安全性基于小病例系列。据我们所知,我们报告了美国首例成人扁桃体切除术安全性的人群水平分析。

目的

描述成人扁桃体切除术的死亡率、并发症和再次手术率。

设计、设置和参与者:回顾性队列研究,纳入了在 2005 年至 2011 年期间美国外科医师学院国家手术质量改进计划数据库中接受扁桃体切除术的 5968 例成年患者的记录。

干预

扁桃体切除术。

主要结局和测量指标

感兴趣的结局包括术后 30 天内的死亡率、并发症和再次手术。统计分析包括卡方检验、t 检验和多变量逻辑回归。

结果

30 天死亡率为 0.03%,并发症发生率为 1.2%,再次手术率为 3.2%。大多数患者的主要诊断为慢性扁桃体炎和/或腺样体炎(82.9%),最常见的并发症为肺炎(占所有并发症的 27%)、尿路感染(27%)和浅表部位感染(16%)。再次手术的患者更可能为男性(54.0%比 32.4%;P < .001)、白人(84.8%比 75.3%;P = .02)或住院患者(24.3%比 14.3%;P < .001),且更有可能发生术后并发症(5.3%比 1.1%;P < .001)。多变量分析显示,男性(比值比[OR],2.30[95%置信区间,1.67-3.15])、住院状态(OR,1.52[95%置信区间,1.04-2.22])和术后并发症(OR,4.58[95%置信区间,2.11-9.93])是再次手术的独立危险因素。

结论和相关性

在美国,成人扁桃体切除术是一种安全的手术,死亡率和发病率都较低。最常见的扁桃体切除术后并发症为感染性病因,并发症与再次手术的需要独立相关。

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