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普通外科出院后并发症与再次手术及死亡率的关联

Association of postdischarge complications with reoperation and mortality in general surgery.

作者信息

Kazaure Hadiza S, Roman Sanziana A, Sosa Julie A

出版信息

Arch Surg. 2012 Nov;147(11):1000-7. doi: 10.1001/2013.jamasurg.114.

Abstract

OBJECTIVES

To describe procedure-specific types, rates, and risk factors for postdischarge (PD) complications occurring within 30 days after 21 groups of inpatient general surgery procedures.

DESIGN

Retrospective cohort study.

SETTING

American College of Surgeons National Surgical Quality Improvement Program 2005 through 2010 Participant Use Data Files.

PATIENTS

A total of 551,510 adult patients who underwent one of 21 groups of general surgery procedures in the inpatient setting.

MAIN OUTCOME MEASURES

Postdischarge complications, reoperation, and mortality.

RESULTS

Of 551,510 patients (mean age, 54.6 years), 16.7% experienced a complication; 41.5% occurred PD. Of the PD complications, 75.0% occurred within 14 days PD. Proctectomy (14.5%), enteric fistula repair (12.6%), and pancreatic procedures (11.4%) had the highest PD complication rates. Breast, bariatric, and ventral hernia repair procedures had the highest proportions of complications that occurred PD (78.7%, 69.4%, and 62.0%, respectively). For all procedures, surgical site complications, infections, and thromboembolic events were the most common. Occurrence of an inpatient complication increased the likelihood of a PD complication (12.5% vs 6.2% without an inpatient complication; P < .001). Compared with patients without a PD complication, those with a PD complication had higher rates of reoperation (4.6% vs 17.9%, respectively; P < .001) and death (2.0% vs 6.9%, respectively; P < .001) within 30 days after surgery; those whose PD complication was preceded by an inpatient complication had the highest rates of reoperation (33.7%) and death (24.7%) (all P < .001). After adjustment, PD complications were associated with procedure type, American Society of Anesthesiologists class higher than 3, and steroid use.

CONCLUSIONS

The PD complication rates vary by procedure, are commonly surgical site related, and are associated with mortality. Fastidious, procedure-specific patient triage at discharge as well as expedited patient follow-up could improve PD outcomes.

摘要

目的

描述21组普通外科住院手术后30天内发生的出院后(PD)并发症的特定手术类型、发生率及危险因素。

设计

回顾性队列研究。

设置

美国外科医师学会国家外科质量改进计划2005年至2010年参与者使用数据文件。

患者

共有551,510例成年患者在住院期间接受了21组普通外科手术中的一种。

主要观察指标

出院后并发症、再次手术和死亡率。

结果

在551,510例患者(平均年龄54.6岁)中,16.7%发生了并发症;41.5%发生在出院后。在出院后并发症中,75.0%发生在出院后14天内。直肠切除术(14.5%)、肠瘘修补术(12.6%)和胰腺手术(11.4%)的出院后并发症发生率最高。乳房、减肥和腹疝修补手术出院后发生并发症的比例最高(分别为78.7%、69.4%和62.0%)。对于所有手术,手术部位并发症、感染和血栓栓塞事件最为常见。住院期间发生并发症会增加出院后并发症的可能性(有住院并发症者为12.5%,无住院并发症者为6.2%;P<.001)。与无出院后并发症的患者相比,有出院后并发症的患者在术后30天内再次手术率(分别为4.6%和17.9%;P<.001)和死亡率(分别为2.0%和6.9%;P<.001)更高;那些出院后并发症之前有住院并发症的患者再次手术率(33.7%)和死亡率(24.7%)最高(所有P<.001)。调整后,出院后并发症与手术类型、美国麻醉医师协会分级高于3级以及使用类固醇有关。

结论

出院后并发症发生率因手术而异,通常与手术部位有关,且与死亡率相关。出院时进行严格的、针对特定手术的患者分类以及加快患者随访可改善出院后结局。

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