Department of Orthopedic Surgery, Spine and Scoliosis Service, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021 USA ; Weill Cornell Medical College, New York, NY 10065 USA.
HSS J. 2014 Feb;10(1):25-9. doi: 10.1007/s11420-013-9367-3. Epub 2013 Nov 1.
Measuring Hounsfield units (HUs) from computed tomography (CT) scans has recently been proposed as a tool for assessing vertebral bone quality, as it has been associated with bone mineral density, compressive strength, and fracture risk. Vertebral bone quality is believed to be an important determinant of outcome and complication rates following spine surgery and potentially influences success of interbody spinal fusion.
QUESTIONS/PURPOSES: The purpose of this study was to investigate the association between HU on CT scans and fusion success in patients with lateral transpsoas surgery for lumbar interbody fusion (LIF).
The CT scans of 28 patients with a combined 52 levels of stand-alone LIF were evaluated at a minimum of 12 weeks postoperatively. Coronal and sagittal images were evaluated for evidence of fusion, and HU values were collected from axial images. HU measurements were also taken from vertebral bodies proximal to the construct to evaluate global bone quality.
Of the 52 LIF levels, 73% were assessed as fused and 27% were nonunited at the time of evaluation. The successful fusion levels had significantly higher HU measurements than the nonunion levels (203.3 vs. 139.8, p < 0.001). Patients with successful fusion constructs also had higher global bone density when vertebral bodies proximal to the construct were compared (133.7 vs. 107.3, p < 0.05).
With the aging population and increasing prevalence of osteoporosis, preoperative assessment of bone quality prior to spinal fusion deserves special consideration. We found that a successful lumbar fusion was associated with patients with higher bone density, as assessed with HU, both globally and within the fusion construct, as compared to patients with CT evidence of nonunion.
最近有人提出,从计算机断层扫描(CT)扫描中测量体素值(Hounsfield units,HU)可作为评估椎体骨质量的一种手段,因为它与骨密度、抗压强度和骨折风险有关。人们认为椎体骨质量是脊柱手术后结果和并发症发生率的重要决定因素,并可能影响椎间融合的成功率。
问题/目的:本研究旨在探讨 CT 扫描 HU 值与腰椎侧前方经椎间孔椎体间融合术(lateral transpsoas surgery for lumbar interbody fusion,LIF)患者融合成功率的关系。
对 28 例接受单纯 LIF 患者的 52 个节段 CT 扫描进行评估,术后至少 12 周进行评估。对冠状位和矢状位图像进行融合评估,并采集轴向图像的 HU 值。还从临近融合器的椎体处采集 HU 值,以评估整体骨质量。
52 个 LIF 节段中,73%被评估为融合,27%未融合。成功融合的节段 HU 值明显高于未融合的节段(203.3 比 139.8,p<0.001)。与非融合节段相比,融合成功节段的临近椎体的骨密度也更高(133.7 比 107.3,p<0.05)。
随着人口老龄化和骨质疏松症发病率的增加,脊柱融合术前对骨质量的评估应引起特别关注。我们发现,与 CT 检查显示非融合的患者相比,HU 值较高的患者(即整体和融合器内的骨密度较高的患者)更容易成功融合。