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腹腔镜治疗子宫内膜异位症及其对生活质量的影响:一项使用EHP - 5子宫内膜异位症专用简表问卷的回顾性研究

Laparoscopic treatment of endometriosis and effects on quality of life: a retrospective study using the short form EHP-5 endometriosis specific questionnaire.

作者信息

Minas V, Dada T

机构信息

Department of Obstetrics and Gynaecology, Stoke Mandeville Hospital , Mandeville Road, Aylesbury , UK.

出版信息

J Obstet Gynaecol. 2014 May;34(4):336-40. doi: 10.3109/01443615.2013.874409. Epub 2014 Jan 31.

Abstract

Complete surgical eradication is considered the mainstay of treatment for endometriosis. The aim of the present study was to investigate patients' own assessment of whether their laparoscopic treatment made a difference to their quality of life, as well as to assess local recurrence rates. We performed a retrospective analysis of 49 women who had laparoscopic treatment for endometriosis at our unit between 1 January 2008 and 1 January 2010. Patients were sent the Short Form EHP-5 questionnaire and asked to score their quality of life in relation to endometriosis symptoms, prior to the surgery and up to 48 months afterwards. Subgroup analysis of stage I/II and stage III/IV disease was performed as well as stratification of the period post-operation into 12-24, 25-36 and 37-48 months for follow-up analysis. Overall, the patients reported improvement in quality of life scores with a significant drop in mean scores from 46.9 pre- to 27.5 post-surgery, signifying benefits from the surgical intervention. All subgroups reported improvement in quality of life scores. The overall symptom recurrence rate was 18.3%. We conclude that patients, post-laparoscopic treatment of endometriosis, experience significant improvement in their quality of life, regardless of stage and this can be quantified and qualified.

摘要

手术彻底切除被认为是子宫内膜异位症治疗的主要方法。本研究的目的是调查患者对腹腔镜治疗是否改善其生活质量的自我评估,以及评估局部复发率。我们对2008年1月1日至2010年1月1日期间在我院接受腹腔镜治疗子宫内膜异位症的49名女性进行了回顾性分析。在手术前及术后长达48个月,向患者发放简化版EHP - 5问卷,要求他们就子宫内膜异位症症状对生活质量进行评分。对I/II期和III/IV期疾病进行了亚组分析,并将术后时间分为12 - 24个月、25 - 36个月和37 - 48个月进行分层随访分析。总体而言,患者报告生活质量评分有所改善,平均评分从术前的46.9显著降至术后的27.5,表明手术干预带来了益处。所有亚组均报告生活质量评分有所改善。总体症状复发率为18.3%。我们得出结论,子宫内膜异位症患者在接受腹腔镜治疗后,无论处于何阶段,生活质量均有显著改善,且这可以进行量化和定性。

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