Fauconnier Arnaud, Huchon Cyrille, Chaillou Laura, Aubry Gabrielle, Renouvel Frederique, Panel Pierre
Department of Gynecology and Obstetrics, Centre Hospitalier Intercommunal de Poissy - Saint-Germain, 10 rue du Champ Gaillard, 78103, Poissy, France.
Research Unit EA7285, Risk and Safety in Clinical Medicine for Women and Perinatal Health, Versailles St-Quentin University, Montigny-le-Bretonneux, France.
Qual Life Res. 2017 Jan;26(1):213-220. doi: 10.1007/s11136-016-1346-y. Epub 2016 Jun 23.
The Endometriosis Health Profile 5 (EHP-5) is a short version of an endometriosis-specific quality of life questionnaire. The objective of the study was to assess the psychometric validity of its French version.
A total of 125 patients with histologically proven endometriosis who underwent surgery for painful symptoms and 80 asymptomatic controls completed the EHP-5. Principal components analysis was performed to determine the dimensions of the instrument. Internal consistency was assessed using Cronbach's alpha. Construct validity was assessed by testing the relationship between the EHP-5 and the characteristics of endometriosis.
For each item of EHP-5, endometriosis patients scored significantly higher than control women (p > 0.0001). Eleven items of the EHP-5 were unidimensional with excellent internal consistency (Cronbach's alpha = 0.92), and a summary aggregated index was then constructed. The EHP-5 index was sensitive to the presence of endometriosis, the type, location, severity of the disease, and pain or infertility as the main complaint with effect sizes ranging from 0.48 (95 % CI 0.11-0.85) for superficial endometriosis to 2.56 (95 % CI 2.18-2.93) for deeply infiltrating endometriosis.
The French version of EHP-5 is valid and can be used for reporting patient-orientated outcome in future studies of French-speaking patients with endometriosis.
子宫内膜异位症健康概况问卷5(EHP - 5)是子宫内膜异位症特异性生活质量问卷的简版。本研究的目的是评估其法语版的心理测量效度。
共有125例经组织学证实患有子宫内膜异位症且因疼痛症状接受手术的患者以及80例无症状对照者完成了EHP - 5问卷。进行主成分分析以确定该问卷的维度。使用Cronbach's α评估内部一致性。通过测试EHP - 5与子宫内膜异位症特征之间的关系来评估结构效度。
对于EHP - 5的每个项目,子宫内膜异位症患者的得分显著高于对照女性(p > 0.0001)。EHP - 5的11个项目具有单维度性且内部一致性极佳(Cronbach's α = 0.92),随后构建了一个汇总综合指数。EHP - 5指数对子宫内膜异位症的存在、疾病类型、位置、严重程度以及以疼痛或不孕为主诉的情况敏感,效应大小范围从浅表性子宫内膜异位症的0.48(95% CI 0.11 - 0.85)到深部浸润性子宫内膜异位症的2.56(95% CI 2.18 - 2.93)。
EHP - 5法语版有效,可用于未来法语区子宫内膜异位症患者研究中报告以患者为导向的结局。