Cheung Bernice H K, Ho Ivan C H, Chan Ruth S M, Sea Mandy M M, Woo Jean
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong.
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong.
Adv Food Nutr Res. 2014;71:137-63. doi: 10.1016/B978-0-12-800270-4.00004-3.
With global aging population, age-related cognitive decline becomes epidemic. Lifestyle-related factor is one of the key preventative measures. Dietary pattern analysis which considers dietary complexity has recently used to examine the linkage between nutrition and cognitive function. A priori approach defines dietary pattern based on existing knowledge. Results of several dietary pattern scores were summarized. The heterogeneity of assessment methods and outcome measurements lead to inconsistent results. Posteriori approach derives a dietary pattern independently of the existing nutrition-disease knowledge. It showed a dietary pattern abundant with plant-based food, oily fish, lower consumption of processed food, saturated fat, and simple sugar which appears to be beneficial to cognitive health. Despite inconclusive evidence from both approaches, diet and exercise, beneficial for other diseases, remains to be the two key modifiable factors for cognitive function. Large-scale prospective studies in multiethics population are required to provide stronger evidence in the future.
随着全球人口老龄化，与年龄相关的认知衰退已成为一种流行病。与生活方式相关的因素是关键的预防措施之一。考虑饮食复杂性的饮食模式分析最近已被用于研究营养与认知功能之间的联系。先验方法基于现有知识定义饮食模式。总结了几种饮食模式评分的结果。评估方法和结果测量的异质性导致结果不一致。后验方法独立于现有的营养-疾病知识得出饮食模式。它显示出一种富含植物性食物、油性鱼类、较少食用加工食品、饱和脂肪和单糖的饮食模式，这似乎对认知健康有益。尽管这两种方法的证据都不确凿，但对其他疾病有益的饮食和运动仍然是认知功能的两个关键可改变因素。未来需要在多民族人群中进行大规模前瞻性研究以提供更有力的证据。
