Moyers Michael F, Mah Dennis, Boyer Sean P, Chang Chang, Pankuch Mark
ProCure Proton Therapy Center, Somerset, NJ.
ProCure Proton Therapy Center, Somerset, NJ.
Med Dosim. 2014 Spring;39(1):98-101. doi: 10.1016/j.meddos.2013.10.006.
Since the early 2000s, a small but rapidly increasing number of patients with breast cancer have been treated with proton beams. Some of these patients have had breast prostheses or tissue expanders in place during their courses of treatment. Procedures must be implemented to plan the treatments of these patients. The density, kilovoltage x-ray computed tomography numbers (kVXCTNs), and proton relative linear stopping powers (pRLSPs) were calculated and measured for several test sample devices. The calculated and measured kVXCTNs of saline were 1% and 2.4% higher than the values for distilled water while the calculated RLSP for saline was within 0.2% of the value for distilled water. The measured kVXCTN and pRLSP of the silicone filling material for the test samples were approximately 1120 and 0.935, respectively. The conversion of kVXCTNs to pRLSPs by the treatment planning system standard tissue conversion function is adequate for saline-filled devices but for silicone-filled devices manual reassignment of the pRLSPs is required.
自21世纪初以来,接受质子束治疗的乳腺癌患者数量虽少,但在迅速增加。其中一些患者在治疗过程中已植入乳房假体或组织扩张器。必须实施相关程序来规划这些患者的治疗。对几个测试样品装置计算并测量了密度、千伏X射线计算机断层扫描数值(kVXCTN)和质子相对线性阻止本领(pRLSP)。盐水的计算和测量kVXCTN比蒸馏水的值分别高1%和2.4%,而盐水的计算RLSP在蒸馏水值的0.2%以内。测试样品的硅酮填充材料的测量kVXCTN和pRLSP分别约为1120和0.935。通过治疗计划系统标准组织转换功能将kVXCTN转换为pRLSP对于填充盐水的装置是合适的,但对于填充硅酮的装置则需要手动重新指定pRLSP。