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硅胶填充阴道间隔器在儿童质子治疗中的剂量学优势

Dosimetric Advantages of Silicone-Filled Vaginal Spacers in Pediatric Proton Therapy.

作者信息

Ates Ozgur, Zhao Li, Sobczak David, Hua Chia-Ho, Krasin Matthew J

机构信息

Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.

出版信息

Int J Part Ther. 2022 May 6;9(1):64-70. doi: 10.14338/IJPT-21-00044.1. eCollection 2022 Summer.

DOI:10.14338/IJPT-21-00044.1
PMID:35774486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9238128/
Abstract

We introduce a custom-made silicone-filled vaginal spacer for use during treatment of female patients receiving pelvic proton radiation therapy. Commercially available vaginal dilators can be purchased as hollow objects; when filled with a media, they can act as a beam stopper and/or tissue spacer while pushing uninvolved vaginal wall away from a high-dose region. Dosimetric advantages of these specifically constructed silicone-filled vaginal spacers were investigated when compared to the unaltered commercially available product or no vaginal spacer in pediatric proton therapy.

摘要

我们推出了一种定制的硅胶填充阴道间隔器，用于接受盆腔质子放射治疗的女性患者的治疗过程中。市售的阴道扩张器可以作为中空物体购买；当填充介质时，它们可以作为射束阻挡器和/或组织间隔器，同时将未受影响的阴道壁推离高剂量区域。在儿科质子治疗中，将这些特殊构造的硅胶填充阴道间隔器与未改变的市售产品或不使用阴道间隔器进行比较，研究了其剂量学优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/22d83956d482/i2331-5180-9-1-64-f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/59fbd20a1ef6/i2331-5180-9-1-64-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/83bf2ce7ddab/i2331-5180-9-1-64-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/317d49c22872/i2331-5180-9-1-64-f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/22d83956d482/i2331-5180-9-1-64-f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/59fbd20a1ef6/i2331-5180-9-1-64-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/83bf2ce7ddab/i2331-5180-9-1-64-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/317d49c22872/i2331-5180-9-1-64-f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/995e/9238128/22d83956d482/i2331-5180-9-1-64-f04.jpg

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本文引用的文献

1
A comparative study of prostate PTV margins for patients using hydrogel spacer or rectal balloon in proton therapy.前列腺水凝胶 spacer 与直肠气囊在质子治疗中前列腺 PTV 外放边界的对比研究。
Phys Med. 2021 Jan;81:47-51. doi: 10.1016/j.ejmp.2020.11.033. Epub 2020 Dec 27.
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Successful use of tissue expander and pelvic sling to exclude small bowel for high-dose pelvic irradiation.成功使用组织扩张器和骨盆吊带将小肠排除在高剂量盆腔照射之外。
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A comparison of relative proton stopping power measurements across patient size using dual- and single-energy CT.
使用双能CT和单能CT对不同体型患者的相对质子阻止本领测量进行比较。
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Feasibility of spacers to facilitate postoperative radiotherapy for retroperitoneal sarcomas.间隔物辅助腹膜后肉瘤术后放疗的可行性
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Late effects of pelvic rhabdomyosarcoma and its treatment in female survivors.盆腔横纹肌肉瘤的晚期效应及其在女性幸存者中的治疗
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