Department of Psychiatry, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, New Hampshire, USA.
Department of Psychiatry, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, New Hampshire, USA; Department of Psychiatry, Veterans Affairs National Center for Patient Safety, White River Junction, Vermont, USA.
Brain Stimul. 2014 Mar-Apr;7(2):151-7. doi: 10.1016/j.brs.2013.10.006. Epub 2013 Oct 31.
Post-traumatic stress disorder (PTSD) is a psychiatric condition with significant morbidity and limited treatment options. Transcranial magnetic stimulation (TMS) has been shown to be an effective treatment for mental illnesses including major depressive disorder.
Review effectiveness of TMS for PTSD.
Literature review with descriptions of primary studies as well as meta-analysis of studies with a control group.
Eight primary studies were identified and three studies met criteria for meta-analysis. All studies suggest effectiveness of TMS for PTSD. Additionally, right-sided may be more effective than left-sided treatment, there is no clear advantage in high versus low frequency, and the treatment is generally well tolerated. Meta-analysis shows significant effect size on PTSD symptoms that may be correlated with total number of stimulations.
TMS for PTSD appears to be an effective and well-tolerated treatment that warrants additional study to further define treatment parameters, course, and side effects.
创伤后应激障碍（PTSD）是一种精神疾病，发病率较高，治疗选择有限。经颅磁刺激（TMS）已被证明对包括重度抑郁症在内的精神疾病有效。
综述 TMS 治疗 PTSD 的效果。
对文献进行综述，包括对对照研究的主要研究的描述和荟萃分析。
确定了 8 项主要研究，其中 3 项研究符合荟萃分析标准。所有研究均表明 TMS 对 PTSD 有效。此外，右侧治疗可能比左侧治疗更有效，高频与低频相比没有明显优势，且治疗通常具有良好的耐受性。荟萃分析显示 PTSD 症状的效应量有显著意义，这可能与刺激总数相关。
TMS 治疗 PTSD 似乎是一种有效且耐受性良好的治疗方法，值得进一步研究以进一步确定治疗参数、疗程和副作用。
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