Li Jian-Fang, Lai Dan-Dan, Lin Zhi-Hong, Jiang Tian-Ye, Zhang Ai-Min, Dai Jian-Feng
Department of Gastrointestinal Surgery, the First People's Hospital of Xiaoshan, Hangzhou Normal University, Hangzhou, People's Republic of China.
Surg Laparosc Endosc Percutan Tech. 2014 Feb;24(1):1-11. doi: 10.1097/SLE.0000000000000041.
Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are 2 of the most widely used bariatric procedures today, in this meta-analysis, both techniques were compared for evaluating the efficacy and safety of the treatment of morbid obesity.
Systematic literature search of Cochrane Controlled Trials Register Databases, Medline, Embase, ISI databases, and Chinese Biomedical Literature Database was performed. Statistical analyses were carried out using RevMan software.
Thirty-two recent studies including 6526 patients in total were included in this meta-analysis. Compared with SG, RYGB had significantly better effect in resolving type 2 diabetes mellitus, hypertension, hypercholesterolemia, gastroesophageal reflux disease, and arthritis. However, RYGB had higher incidence of complications and reoperation, and longer operation time than SG.
RYGB was more effective than SG in the resolution of obesity-related comorbidities, SG was a safer procedure with a reduced rate of complications and reoperation.
Roux-en-Y胃旁路术（RYGB）和袖状胃切除术（SG）是当今最广泛使用的两种减肥手术，在这项荟萃分析中，对这两种技术进行了比较，以评估治疗病态肥胖的疗效和安全性。
对Cochrane对照试验注册数据库、Medline、Embase、ISI数据库和中国生物医学文献数据库进行系统的文献检索。使用RevMan软件进行统计分析。
这项荟萃分析纳入了32项近期研究，共6526例患者。与SG相比，RYGB在解决2型糖尿病、高血压、高胆固醇血症、胃食管反流病和关节炎方面效果显著更好。然而，RYGB的并发症和再次手术发生率更高，手术时间也比SG长。
RYGB在解决肥胖相关合并症方面比SG更有效，SG是一种更安全的手术，并发症和再次手术发生率较低。
