National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan.
National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan Department of Psychiatry, Japanese Red Cross Medical Center, Tokyo, Japan.
Behav Neurol. 1994;7(2):97-9. doi: 10.3233/BEN-1994-7209.
Clinical features and results of neuroimagings of an 86 year old woman with the Charles Bonnet syndrome are reported. She had become completely blind bilaterally due to cataracts and glaucoma. Shortly after an operation for cataracts, she developed visual hallucinations which lasted for 22 years. She had no deterioration of intelligence. Computed tomography (CT) and magnetic resonance imaging (MRI) showed moderate generalized atrophy, particularly of the temporal lobes. A serial single photon emission computed tomography (SPECT) study during visual hallucinations demonstrated hyperperfusion in the left temporal region and the basal ganglia and hypoperfusion in the right temporal region. These findings suggest that asymmetrical blood flow, particularly in the temporal regions, may be correlated with visual hallucination in the Charles Bonnet syndrome.
现报道一例 86 岁女性 Charles Bonnet 综合征的神经影像学表现和临床特点。该患者因白内障和青光眼而双侧失明。白内障手术后不久，她出现了持续 22 年的幻视。她的智力没有下降。计算机断层扫描（CT）和磁共振成像（MRI）显示广泛的中度脑萎缩，特别是颞叶。在出现幻视期间进行的一系列单光子发射计算机断层扫描（SPECT）研究显示左侧颞叶和基底节区血流量增加，右侧颞叶血流量减少。这些发现表明，不对称的血流，特别是在颞叶区域，可能与 Charles Bonnet 综合征的幻视有关。
