Choi Eun-Jung, Lee Jung-Kyo, Kang Joong-Koo, Lee Sang-Ahm
Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Arch Neurol. 2005 Mar;62(3):481-4. doi: 10.1001/archneur.62.3.481.
Charles Bonnet syndrome is a rare disorder characterized by complex and recurrent visual hallucinations in elderly patients with visual pathway pathologic defects. To date, to our knowledge, it has not been described in patients undergoing surgical resection for occipital lobe epilepsy due to cortical dysplasia.
To describe a patient who experienced complex visual hallucinations following resection of cortical dysplasia on the right occipital lobe and who was diagnosed as having Charles Bonnet syndrome.
A 35-year-old woman underwent surgical resection for medically intractable epilepsy caused by cortical dysplasia involving the right occipital lobe.
Two months after resection of the epileptogenic zone, complex visual hallucinations in the left visual field not associated with loss of consciousness or delusion developed in the patient. Hallucinations persisted for more than 12 months despite treatment with antiepileptic medications. During hallucination, no electrographic seizures were recorded through long-term video-electroencephalographic monitoring.
Charles Bonnet syndrome may occur in a patient with occipital lobe epilepsy following resection of the diseased brain with a developmental malformation. Charles Bonnet syndrome associated with surgical treatment of occipital lobe epilepsy may have been overlooked.
查尔斯·邦尼特综合征是一种罕见的疾病，其特征为患有视觉通路病理缺陷的老年患者出现复杂且反复的视幻觉。据我们所知，迄今为止，尚未在因皮质发育异常而接受枕叶癫痫手术切除的患者中描述过该综合征。
描述一名在右枕叶皮质发育异常切除术后出现复杂视幻觉并被诊断为患有查尔斯·邦尼特综合征的患者。
一名35岁女性因右枕叶皮质发育异常导致药物难治性癫痫接受了手术切除。
癫痫病灶切除术后两个月，患者在左侧视野出现了不伴有意识丧失或妄想的复杂视幻觉。尽管使用抗癫痫药物治疗，幻觉仍持续了12个月以上。在幻觉发作期间，通过长期视频脑电图监测未记录到脑电图癫痫发作。
查尔斯·邦尼特综合征可能发生在患有发育畸形的病变脑切除术后的枕叶癫痫患者中。与枕叶癫痫手术治疗相关的查尔斯·邦尼特综合征可能一直被忽视。
