Okuno Meiry Fernanda Pinto, Cintra Raíssa Silveira, Vancini-Campanharo Cássia Regina, Batista Ruth Ester Assayag
Einstein (Sao Paulo). 2013 Dec;11(4):462-6. doi: 10.1590/s1679-45082013000400010.
To identify the occurrence of potential drug interactions in prescriptions for adult patients admitted to the Emergency Department of Hospital São Paulo.
A cross-sectional and descriptive study. Its sample consisted of 200 medical prescriptions. The analysis of drug interactions was performed using the Drugs.com database, where they are classified according to severity of interaction as severe, moderate, mild and without interaction.
The number of drugs in prescriptions ranged from 2 to 19, and the average per prescription was 4.97 drugs. A total of 526 potential drug interactions were identified in 159 prescriptions (79.5%); in that, 109 were severe, 354 moderate, 63 mild interactions, and 41 showed no interaction.
This study demonstrated potential drug interactions in 79.5% of prescriptions examined in the Emergency Department. Drug interactions can occur at any time when using medications and, during this working process, the nursing staff is involved in several steps. Therefore, training the nursing staff for the rational use of drugs can increase safety of care delivered to patients.
确定圣保罗医院急诊科收治的成年患者处方中潜在药物相互作用的发生情况。
一项横断面描述性研究。其样本包括200份医疗处方。使用Drugs.com数据库进行药物相互作用分析，在该数据库中，药物相互作用根据严重程度分为严重、中度、轻度和无相互作用。
处方中的药物数量从2种到19种不等，每份处方平均有4.97种药物。在159份处方（79.5%）中总共识别出526种潜在药物相互作用；其中，109种为严重相互作用，354种为中度相互作用，63种为轻度相互作用，41种无相互作用。
本研究表明，在急诊科检查的处方中，79.5%存在潜在药物相互作用。使用药物时随时可能发生药物相互作用，在这个过程中，护理人员参与多个步骤。因此，培训护理人员合理用药可提高为患者提供的护理安全性。
