α-甲硅烷基砜/三氟甲磺酸酯/氯代酮作为氧化炔等价物：用于合成杂环化合物的氧化还原中性铑(III)催化 C-H 活化
α-MsO/TsO/Cl ketones as oxidized alkyne equivalents: redox-neutral rhodium(III)-catalyzed C-H activation for the synthesis of N-heterocycles.
机构信息
Westfälische Wilhelms-Universität Münster, Organisch-Chemisches Institut, Corrensstrasse 40, 48149 Münster (Germany) http://www.uni-muenster.de/Chemie.oc/glorius/
出版信息
Angew Chem Int Ed Engl. 2014 Mar 3;53(10):2754-8. doi: 10.1002/anie.201310272. Epub 2014 Feb 2.
α-Halo and pseudohalo ketones are used for the first time as C(sp(3))-based electrophiles in transition-metal-catalyzed C-H activation and as oxidized alkyne equivalents in Rh(III)-catalyzed redox-neutral annulations to generate diverse N-heterocycles. This transformation is efficient and scalable. Due to the mild reaction conditions, a variety of functional groups could be tolerated.
α-卤代和拟卤代酮首次被用作过渡金属催化的 C-H 活化中的 C(sp(3))-基亲电试剂，以及 Rh(III)催化的氧化炔等价物在氧化还原中性环化反应中生成各种 N-杂环。这种转化是高效和可扩展的。由于反应条件温和，各种官能团都可以耐受。
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