Pews-Davtyan Anahit, Fang Xianjie, Jackstell Ralf, Spannenberg Anke, Baumann Wolfgang, Franke Robert, Beller Matthias
Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Str. 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-131.
Chem Asian J. 2014 Apr;9(4):1168-74. doi: 10.1002/asia.201301636. Epub 2014 Feb 2.
Carbocyclic and N-heterocyclic analogues of the industrially applied ligand bis(di-tert-butylphosphinomethyl)benzene (1) have been synthesized in moderate to very good yields. The new ligands are based on benzene, tetralin, lutidine, pyrazine, quinoxaline, and maleimide backbones. Electronic and steric variations of the phosphorous donor sites were performed. As a benchmark reaction, the palladium-catalyzed methoxycarbonylation of 1-octene has been tested. Ester yields up to 64% and high linear selectivities up to 92% were achieved.
已以中等到非常好的产率合成了工业应用配体双（二叔丁基膦甲基）苯（1）的碳环和N-杂环类似物。新配体基于苯、四氢化萘、二甲基吡啶、吡嗪、喹喔啉和马来酰亚胺骨架。对磷供体位点进行了电子和空间变化。作为基准反应，测试了钯催化的1-辛烯甲氧基羰基化反应。酯产率高达64%，线性选择性高达92%。
