Gao Jinsuo, Zhang Xueying, Xu Shutao, Tan Feng, Li Xinyong, Zhang Yaobin, Qu Zhenping, Quan Xie, Liu Jian
Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, Dalian University of Technology, Linggong Road 2, Dalian 116024 (P.R. China).
Chemistry. 2014 Feb 10;20(7):1957-63. doi: 10.1002/chem.201303778. Epub 2013 Nov 13.
Pharmaceutical antibiotics are not easily removed from water by conventional water-treatment technologies and have been recognized as new emerging pollutants. Herein, we report the synthesis of clickable azido periodic mesoporous organosilicas (PMOs) and their use as adsorbents for the adsorption of antibiotics. Ethane-bridged PMOs, functionalized with azido groups at different densities, were synthesized by the co-condensation of 1,2-bis(trimethoxysilyl)ethane (BTME) and 3-azidopropyltrimethoxysilane (AzPTMS), in the presence of nonionic-surfactant triblock-copolymer P123, in an acidic medium. Four different alkynes were conjugated to azide-terminated PMOs by means of an efficient click reaction. The clicked PMOs showed improved adsorption capacity (241 μg g(-1)) for antibiotics (ciprofloxacin hydrochloride) compared with azido-functionalized PMOs because of the enhanced π-π stacking interactions. These results indicate that click reactions can introduce multifunctional groups onto PMOs, thus demonstrating the great potential of PMOs for environmental applications.
药用抗生素不易通过传统水处理技术从水中去除，已被视为新兴污染物。在此，我们报道了可点击的叠氮基周期性介孔有机硅（PMO）的合成及其作为吸附剂用于吸附抗生素的应用。通过1,2-双（三甲氧基硅基）乙烷（BTME）和3-叠氮基丙基三甲氧基硅烷（AzPTMS）在非离子表面活性剂三嵌段共聚物P123存在下于酸性介质中共缩聚，合成了不同密度叠氮基官能化的乙烷桥连PMO。通过高效点击反应将四种不同的炔烃与叠氮基封端的PMO共轭。与叠氮基官能化的PMO相比，点击后的PMO对抗生素（盐酸环丙沙星）表现出更高的吸附容量（241 μg g⁻¹），这是由于增强的π-π堆积相互作用。这些结果表明点击反应可将多功能基团引入PMO，从而证明了PMO在环境应用中的巨大潜力。
