Murthy Vishal D, Gaitero Luis, Monteith Gabrielle
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
Can Vet J. 2014 Feb;55(2):169-74.
The potential link between degenerative changes seen on magnetic resonance imaging (MRI) in osseous-associated cervical spondylomyelopathy (OA-CSM) and clinical signs has not been explored. Our goal was to retrospectively evaluate MRI findings, while investigating potential correlations between these changes, signalment, and clinical signs. Twenty-six dogs diagnosed with OA-CSM were included in the study. Clinical signs were converted into a Modified Frankel Score (MFS) and MRI findings were assessed and graded. Giant breeds had multiple compressed sites and presented at a younger age than large breeds, suggesting a different underlying pathophysiology. Spinal cord compression, most commonly bilateral, was present in 36.8% of intervertebral spaces. Synovial fluid loss and articular process sclerosis were the most common degenerative changes. Most dogs showed identical MFS scores, and no significant correlations were found between MFS and MRI changes. More detailed functional scales should be used to investigate this in the future.
在骨相关性颈椎病(OA-CSM)中,磁共振成像(MRI)所见的退行性改变与临床体征之间的潜在联系尚未得到探讨。我们的目标是回顾性评估MRI结果,同时研究这些改变、信号特征和临床体征之间的潜在相关性。26只被诊断为OA-CSM的犬纳入本研究。临床体征被转换为改良Frankel评分(MFS),并对MRI结果进行评估和分级。巨型犬种有多个受压部位,且比大型犬种发病年龄更小,提示存在不同的潜在病理生理学机制。36.8%的椎间隙存在脊髓压迫,最常见为双侧压迫。滑液丢失和关节突硬化是最常见的退行性改变。大多数犬的MFS评分相同,且未发现MFS与MRI改变之间存在显著相关性。未来应使用更详细的功能量表对此进行研究。