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Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5/class I transactivator.
J Immunol. 2012 Jul 15;189(2):516-20. doi: 10.4049/jimmunol.1200064. Epub 2012 Jun 18.
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Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins.
J Biol Chem. 2012 Jul 13;287(29):24294-303. doi: 10.1074/jbc.M112.364604. Epub 2012 May 29.
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NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens.
Cell Res. 2012 May;22(5):836-47. doi: 10.1038/cr.2012.56. Epub 2012 Apr 10.
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NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression.
J Immunol. 2012 May 15;188(10):4951-8. doi: 10.4049/jimmunol.1103160. Epub 2012 Apr 6.
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Enhanced TLR-induced NF-κB signaling and type I interferon responses in NLRC5 deficient mice.
Cell Res. 2012 May;22(5):822-35. doi: 10.1038/cr.2012.53. Epub 2012 Apr 3.
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NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells.
J Immunol. 2012 Apr 15;188(8):3820-8. doi: 10.4049/jimmunol.1102671. Epub 2012 Mar 12.
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The nucleotide-binding domain of NLRC5 is critical for nuclear import and transactivation activity.
Biochem Biophys Res Commun. 2012 Feb 24;418(4):786-91. doi: 10.1016/j.bbrc.2012.01.104. Epub 2012 Jan 28.
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NLRC5: a newly discovered MHC class I transactivator (CITA).
Microbes Infect. 2012 Jun;14(6):477-84. doi: 10.1016/j.micinf.2011.12.007. Epub 2011 Dec 22.
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NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.
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NLRC5 limits the activation of inflammatory pathways.
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