Mikolasević Ivana, Radić Mladen, Milić Sandra, Stimac Davor
Zavod za gastroenterologiju, Klinika za internu medicinu, Medicinski fakultet Sveucilista u Rijeci, Klinicki bolnicki center Rijeka.
Lijec Vjesn. 2013 Nov-Dec;135(11-12):322-5.
Recently, acute-on-chronic liver failure has been recognized as a specific and unique clinical form of liver failure (usually related to acute insult) in patients with previously known or unknown compensated chronic liver disease. Its main feature is the reversibility, and high short-mortality due to multiorgan failure (MOF) in the absence of liver support system devices and/or liver transplantation. This article aims to introduce the definition and better understanding of this newly developed and unique profile of liver failure.
最近,慢加急性肝衰竭已被公认为是先前已知或未知的代偿性慢性肝病患者发生肝衰竭(通常与急性损伤有关)的一种特殊且独特的临床形式。其主要特征是具有可逆性,并且在缺乏肝支持系统设备和/或肝移植的情况下,由于多器官功能衰竭(MOF)导致短期死亡率很高。本文旨在介绍这种新出现的独特肝衰竭类型的定义,并增进对它的了解。