[钙稳态]

[Calcium homeostasis].

作者信息

Wieliczko Monika, Matuszkiewicz-Rowińska Joanna

机构信息

Katedra i Klinika Nefrologii, Dializoterapii i Chorób Wewnetrznych, Warszawski Uniwersytet Medyczny.

出版信息

Wiad Lek. 2013;66(4):299-302.

PMID:24490481

Abstract

There is approximately 1000-1500 g of calcium in the human body, 98-99% of this being in the form of hydroxyapatite in bone. Serum ionized calcium is tightly regulated through a complex interplay of parthormone (PTH), calcitriol (1.25(OH)2,D), and ionized calcium itself, acting through their receptors mostly in parathyroids, intestine, bone and kidney. In the review role of those factors and organs in calcium homeostasis is shortly discussed.

摘要

人体中约有1000 - 1500克钙，其中98 - 99%以骨中羟基磷灰石的形式存在。血清离子钙通过甲状旁腺激素（PTH）、骨化三醇（1,25(OH)₂D）和离子钙自身之间复杂的相互作用而受到严格调节，它们主要通过其在甲状旁腺、肠道、骨骼和肾脏中的受体发挥作用。本文简要讨论了这些因素和器官在钙稳态中的作用。