Jones R E, Willis S, Innes D J, Wanebo H J
Department of Surgery, University of Virginia Medical Center, Charlottesville.
Am J Surg. 1988 Jan;155(1):118-23. doi: 10.1016/s0002-9610(88)80268-x.
A retrospective review of 28 patients with primary gastric lymphoma was performed to determine the optimal treatment modality. The presenting signs and symptoms resembled peptic ulcer disease or gastric carcinomas. The majority of the lymphomas were of the diffuse histiocytic subtype. There was a 75 percent resectability rate in those patients operated on. Palliative resection produced a 5 year duration of survival of 28 percent and curative resection, 43 percent. Eighteen patients underwent a subtotal gastrectomy, and a total of 10 patients presented with stage I disease. The longest median duration of survival at last follow-up was 32 months for patients with stage IB disease compared with a median duration of survival of 8 months for those with stage III disease. Adjuvant radiotherapy and chemotherapy may improve survival after a curative resection is performed if there is serosal penetration or nodal involvement.
对28例原发性胃淋巴瘤患者进行了回顾性研究，以确定最佳治疗方式。其临床表现和症状类似于消化性溃疡病或胃癌。大多数淋巴瘤为弥漫性组织细胞亚型。接受手术的患者中，可切除率为75%。姑息性切除术后5年生存率为28%，根治性切除术后为43%。18例患者接受了胃大部切除术，共有10例患者为Ⅰ期疾病。末次随访时，IB期疾病患者的最长中位生存期为32个月，而Ⅲ期疾病患者的中位生存期为8个月。如果存在浆膜侵犯或淋巴结受累，辅助放疗和化疗可能会改善根治性切除术后的生存率。
