Price Matthew, Kearns Megan, Houry Debra, Rothbaum Barbara O
Department of Psychology, University of Vermont.
Centers for Disease Control and Prevention.
J Consult Clin Psychol. 2014 Apr;82(2):336-41. doi: 10.1037/a0035537. Epub 2014 Feb 3.
Recent data have supported the use of an early exposure intervention to promote a reduction in acute stress and posttraumatic stress disorder (PTSD) symptoms after trauma exposure. The present study explored a comprehensive predictive model that included history of trauma exposure, dissociation at the time of the trauma and early intervention, and physiological responses (cortisol and heart rate) to determine which variables were most indicative of reduced PTSD symptoms for an early intervention or treatment as usual.
Participants (n = 137) were randomly assigned to the early intervention condition (n = 68) or assessment-only condition (n = 69) while receiving care at the emergency department of a Level 1 trauma center. Follow-up assessments occurred at 4 and 12 weeks posttrauma.
Findings suggested that dissociation at the time of the 1st treatment session was associated with reduced response to the early intervention. No other predictors were associated with treatment response. For treatment as usual, cortisol levels at the time of acute care and dissociation at the time of the traumatic event were positively associated with PTSD symptoms.
Dissociation at the time at which treatment starts may indicate poorer response to early intervention for PTSD. Similarly, dissociation at the time of the event was positively related to PTSD symptoms in those who received treatment as usual.
近期数据支持采用早期暴露干预来促进创伤暴露后急性应激和创伤后应激障碍(PTSD)症状的减轻。本研究探索了一个综合预测模型,该模型包括创伤暴露史、创伤时的解离和早期干预,以及生理反应(皮质醇和心率),以确定哪些变量最能表明早期干预或常规治疗对PTSD症状减轻的指示作用。
137名参与者在一级创伤中心急诊科接受治疗时,被随机分配到早期干预组(n = 68)或仅评估组(n = 69)。在创伤后4周和12周进行随访评估。
研究结果表明,第一次治疗时的解离与对早期干预的反应降低有关。没有其他预测因素与治疗反应相关。对于常规治疗,急性护理时的皮质醇水平和创伤事件时的解离与PTSD症状呈正相关。
治疗开始时的解离可能表明对PTSD早期干预的反应较差。同样,事件发生时的解离与接受常规治疗者的PTSD症状呈正相关。