Vanguri Poornima, Brengman Matthew, Oiticica Claudio, Wickham Edmond P, Bean Melanie K, Lanning David A
Department of Surgery, Virginia Commonwealth University, Virginia.
Advanced Surgical Partners of Virginia, Parham Doctors Hospital, Virginia.
Semin Pediatr Surg. 2014 Feb;23(1):24-30. doi: 10.1053/j.sempedsurg.2013.10.018. Epub 2013 Nov 1.
Childhood obesity is a significant problem. Due in part to suboptimal weight loss with lifestyle intervention alone, bariatric surgery, combined with ongoing lifestyle changes, has become a favorable approach in adolescents with severe obesity and weight-related comorbidities and is associated with effective weight loss and reducing weight-related comorbidities. Laparoscopic greater curvature plication is a promising new bariatric surgical procedure that has been shown to be effective in adults with severe obesity but has not been evaluated in the adolescent population. Gastric plication may be a particularly attractive approach for the adolescent patient as it is potentially reversible, does not involve the surgical removal of tissue, and is without a significant malabsorptive component. Our team has obtained approval from our Institutional Review Board to perform a laparoscopic greater curvature plication on 30 adolescent patients with severe obesity and study its effect on weight loss, metabolic effects, and psychological functioning in the setting of a multidisciplinary program. Results of this study, including comprehensive clinical and psychological data collected over a 3.5-year span, will inform larger prospective investigations comparing the laparoscopic greater curvature plication and other bariatric operations in the adolescent population.
儿童肥胖是一个重大问题。部分由于仅通过生活方式干预减肥效果欠佳,减肥手术结合持续的生活方式改变,已成为治疗重度肥胖及与体重相关合并症青少年的一种有利方法,且与有效减重及减轻与体重相关的合并症有关。腹腔镜大弯折叠术是一种有前景的新型减肥手术,已证明对重度肥胖成人有效,但尚未在青少年群体中进行评估。胃折叠术对青少年患者可能是一种特别有吸引力的方法,因为它可能是可逆的,不涉及组织切除,且没有明显的吸收不良成分。我们的团队已获得机构审查委员会的批准,对30名重度肥胖青少年患者进行腹腔镜大弯折叠术,并在多学科项目背景下研究其对体重减轻、代谢效应和心理功能的影响。这项研究的结果,包括在3.5年期间收集的全面临床和心理数据,将为比较腹腔镜大弯折叠术与青少年群体中其他减肥手术的更大规模前瞻性研究提供参考。