Department of Biostatistics, Obesity Research Chair, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Ann Surg. 2012 Aug;256(2):266-73. doi: 10.1097/SLA.0b013e318251e92b.
To report experience with laparoscopic sleeve gastrectomy (LSG) in 108 severely obese children and adolescents.
Obesity during childhood and adolescence can be accompanied by serious long-term adverse health and longevity outcomes. With increased use of bariatric surgery to treat obesity in these patients, diverse guidelines have been published, most of which exclude children aged younger than 14 years. Few reports describe LSG in children and adolescents, delaying determining its safety and effectiveness and developing guidance regarding its use.
A retrospective review of LSG performed from March 2008 through February 2011 by a single surgeon at King Saud University Hospitals, Riyadh, Saudi Arabia, included 108 patients aged 5 through 21 years.
Patients attending follow-up visits at 3 (n = 88), 6 (n = 76), 12 (n = 41), and 24 (n = 8) months postoperatively experienced median excess weight loss (EWL) of 28.9%, 48.1%, 61.3%, and 62.3%, respectively. At 6 and 12 months follow-up, 42.1% (n = 32) and 73.2% (n = 30) of patients achieved at least 50% EWL, whereas 7.9% (n = 6) and 4.9% (n = 2) had 25% or less EWL, respectively. There were no serious postoperative complications and no adverse sequelae developed during the current follow-up. Available comorbidity data indicate resolution of dyslipidemia, 21 of 30 (70.0%); hypertension, 27 of 36 (75.0%); prehypertension, 15 of 18 (83.3%); symptoms of obstructive sleep apnea, 20 of 22 (90.9%); diabetes, 15 of 16 (93.8%); and prediabetes, 11 of 11 (100.0%).
LSG resulted in successful short-term weight loss in more than 90% of pediatric patients and 70% or more comorbidity resolution during up to 24 months of follow-up. Long-term data are necessary to evaluate persistence of weight loss and maturation to adulthood.
报告 108 例严重肥胖儿童和青少年行腹腔镜袖状胃切除术(LSG)的经验。
儿童和青少年时期的肥胖可伴随严重的长期健康和长寿不良后果。随着减重手术治疗这些患者肥胖的应用增加,已发布了多项指南,但其中大多数都排除了年龄小于 14 岁的儿童。很少有报告描述儿童和青少年的 LSG,这延迟了确定其安全性和有效性的时间,并制定了关于其使用的指导意见。
对 2008 年 3 月至 2011 年 2 月期间由沙特阿拉伯利雅得沙特国王大学医院的一位外科医生行 LSG 的 108 例 5 至 21 岁患者进行回顾性分析。
接受术后 3(n = 88)、6(n = 76)、12(n = 41)和 24(n = 8)个月随访的患者,术后中位体重减轻量(EWL)分别为 28.9%、48.1%、61.3%和 62.3%。在 6 个月和 12 个月的随访中,42.1%(n = 32)和 73.2%(n = 30)的患者达到至少 50%EWL,而分别有 7.9%(n = 6)和 4.9%(n = 2)的患者 EWL 减少了 25%或更少。没有发生严重的术后并发症,且在目前的随访中没有出现不良后遗症。现有的合并症数据表明,血脂异常得到缓解(30 例中的 21 例,70.0%)、高血压缓解(36 例中的 27 例,75.0%)、高血压前期缓解(18 例中的 15 例,83.3%)、阻塞性睡眠呼吸暂停症状缓解(22 例中的 20 例,90.9%)、糖尿病缓解(16 例中的 15 例,93.8%)和糖尿病前期缓解(11 例中的 11 例,100.0%)。
LSG 可使超过 90%的儿科患者在 24 个月的随访中获得成功的短期减重,70%或更多的患者合并症得到缓解。需要长期数据来评估体重减轻的持续时间和成熟度到成年期。