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腹腔镜胃大弯折叠术(LGGCP)有未来吗?对 44 例患者的回顾。

Is there a future for Laparoscopic Gastric Greater Curvature Plication (LGGCP)? a review of 44 patients.

机构信息

Département de Chirurgie, Division de Chirurgie Bariatrique, Hôpital du Sacré-Coeur de Montréal, Université de Montréal, 5400 boul. Gouin ouest Montréal, Québec, H4J 1C5, Canada.

出版信息

Obes Surg. 2013 Sep;23(9):1397-403. doi: 10.1007/s11695-013-0934-y.

DOI:10.1007/s11695-013-0934-y
PMID:23575554
Abstract

BACKGROUND

Laparoscopic gastric greater curvature plication (LGGCP) is a new restrictive weight loss procedure.

METHODS

Between February 2011 and June 2012, 57 patients underwent LGGCP. Thirteen had it associated with a lap band and were excluded from the study. Data was collected through routine follow-up. Demographics, complications, and percentage of excess weight loss (% EWL) were determined.

RESULTS

Forty-four patients underwent LGGCP, 40 women and 4 men with a mean age of 40 years (range, 18-72), a mean body mass index of 38 kg/m(2) (range, 35-46). Comorbidities included 2 diabetes mellitus, 11 hypertension, 8 hyperlipidaemia, and 8 obstructive sleep apnea. The mean operative time was 106 min (range, 60-180) and mean duration of hospital stay was 18 h (range, 12-168). Operative complications included one subphrenic abscess, one gastrogastric hernia, and one acute respiratory distress syndrome. Thirty patients experienced strong restriction with nausea and vomiting for the first 10 days (79.5 %). Eleven patients (25.0 %) came back with intractable nausea and vomiting, and were hospitalized, or had their hospital stay prolonged. Four patients needed early reversal of gastric plication (9 %). There was no postoperative death. The mean postoperative % EWL was 30.6 % (n = 40), 57.0 % (n = 24), 50.7 % (n = 13) at 1, 6, and 12 months, respectively.

CONCLUSIONS

LGGCP yields an acceptable weight loss compared to other restrictive procedures, but with a higher readmission rate for postoperative nausea and vomiting, or even reversal of plication. We advocate more studies to evaluate safety and effectiveness.

摘要

背景

腹腔镜胃大弯折叠术(LGGCP)是一种新的限制性减肥手术。

方法

2011 年 2 月至 2012 年 6 月,57 例患者接受了 LGGCP。其中 13 例与胃带联合进行,因此被排除在研究之外。通过常规随访收集数据。确定了人口统计学、并发症和体重减轻百分比(%EWL)。

结果

44 例患者接受了 LGGCP,其中 40 例为女性,4 例为男性,平均年龄为 40 岁(范围,18-72 岁),平均体重指数为 38kg/m2(范围,35-46)。合并症包括 2 型糖尿病、11 例高血压、8 例高脂血症和 8 例阻塞性睡眠呼吸暂停。手术时间平均为 106 分钟(范围,60-180 分钟),平均住院时间为 18 小时(范围,12-168 小时)。手术并发症包括膈下脓肿 1 例、胃胃疝 1 例和急性呼吸窘迫综合征 1 例。30 例患者在最初 10 天出现强烈的限制和恶心呕吐(79.5%)。11 例(25.0%)患者因难治性恶心呕吐而返回,需要住院或延长住院时间。4 例患者需要早期反转胃折叠(9%)。术后无死亡。40 例患者术后平均%EWL 为 30.6%(n=40),24 例患者分别为 57.0%(n=24)、50.7%(n=13),分别为术后 1、6 和 12 个月。

结论

与其他限制性手术相比,LGGCP 可获得可接受的减重效果,但术后恶心呕吐的再入院率较高,甚至需要反转折叠。我们提倡进行更多的研究来评估安全性和有效性。

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