Eickhoff Christa, Mei Jian M, Martinez Jorge, Little Dustin
Department of Medicine, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20889.
Senior Medical Officer Onboard, USS America (LHA6), San Diego, CA.
Mil Med. 2014 Feb;179(2):e259-62. doi: 10.7205/MILMED-D-13-00478.
Renal infarction (RI) is rare, and usually occurs in patients with associated comorbidities. The majority of reported cases have presented with laboratory abnormalities, most notably leukocytosis and elevated lactate dehydrogenase (LDH). A 50-year-old active duty white male nonsmoker without medical history presented with flank pain. Urinalysis, complete blood count, LDH, and serum creatinine were normal. Contrast-enhanced computed tomography of the abdomen and pelvis showed a right-sided RI. The patient was admitted to the hospital and anticoagulated. Laboratory values remained normal, and a comprehensive workup failed to reveal an etiology for his RI. RI is rare, and affected patients often present with symptoms similar to more common conditions such as lumbago or nephrolithiasis. Elevated LDH may be a clue to the diagnosis, but unlike 92% of the reviewed cases, our patient presented with a normal value. This case suggests that clinicians should consider RI in patients with persistent symptoms for whom more common causes of flank pain have been excluded; including in nonsmoking patients without apparent risk factors for infarction who present with a normal LDH and no leukocytosis.
肾梗死(RI)较为罕见,通常发生于伴有合并症的患者。大多数已报道病例存在实验室检查异常,最显著的是白细胞增多和乳酸脱氢酶(LDH)升高。一名50岁现役白人男性非吸烟者,无病史,出现胁腹疼痛。尿液分析、全血细胞计数、LDH和血清肌酐均正常。腹部和盆腔增强计算机断层扫描显示右侧肾梗死。患者入院并接受抗凝治疗。实验室检查值仍正常,全面检查未能揭示其肾梗死的病因。肾梗死很罕见,受影响的患者常表现出与更常见病症(如腰痛或肾结石)相似的症状。LDH升高可能是诊断的线索,但与92%的综述病例不同,我们的患者LDH值正常。该病例表明,对于已排除更常见胁腹疼痛原因的持续性症状患者,临床医生应考虑肾梗死;包括无明显梗死危险因素、LDH正常且无白细胞增多的非吸烟患者。