在自行服用合成毒品α-吡咯烷戊酮后遭受持续约束后猝死。 - Suppr

Sudden death after sustained restraint following self-administration of the designer drug α-pyrrolidinovalerophenone.

作者信息

Nagai Hisashi, Saka Kanju, Nakajima Makoto, Maeda Hidyuki, Kuroda Ryohei, Igarashi Atsuko, Tsujimura-Ito Takako, Nara Akina, Komori Masatomo, Yoshida Ken-Ichi

机构信息

Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, Japan.

出版信息

Int J Cardiol. 2014 Mar 1;172(1):263-5. doi: 10.1016/j.ijcard.2013.12.262. Epub 2014 Jan 15.

DOI:10.1016/j.ijcard.2013.12.262

PMID:24491861

Abstract

摘要

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Sudden death after sustained restraint following self-administration of the designer drug α-pyrrolidinovalerophenone.

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引用本文的文献

Acute pharmacological effects of α-PVP in humans: a naturalistic observational study.

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Arch Toxicol. 2021 Sep;95(9):2895-2940. doi: 10.1007/s00204-021-03083-3. Epub 2021 Jun 8.

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Designer drugs: mechanism of action and adverse effects.

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Sudden death after sustained restraint following self-administration of the designer drug α-pyrrolidinovalerophenone.

Int J Cardiol. 2014 Mar 1;172(1):263-5. doi: 10.1016/j.ijcard.2013.12.262. Epub 2014 Jan 15.

Sudden cardiac death complicating acute myocardial infarction following synthetic cannabinoid use.

Intern Med J. 2014 Sep;44(9):934-6. doi: 10.1111/imj.12521.

DARK Classics in Chemical Neuroscience: α-Pyrrolidinovalerophenone ("Flakka").

ACS Chem Neurosci. 2019 Jan 16;10(1):168-174. doi: 10.1021/acschemneuro.8b00525. Epub 2018 Nov 26.

GC-MS analysis of the designer drug α-pyrrolidinovalerophenone and its metabolites in urine and blood in an acute poisoning case.

Forensic Sci Int. 2016 Feb;259:e14-9. doi: 10.1016/j.forsciint.2015.12.020. Epub 2015 Dec 20.

Sudden cardiac death associated with methylone use.

Am J Forensic Med Pathol. 2013 Mar;34(1):26-8. doi: 10.1097/PAF.0b013e31827ab5da.

A Fatal Case of Pentedrone and α-Pyrrolidinovalerophenone Poisoning.

J Anal Toxicol. 2015 May;39(4):324-9. doi: 10.1093/jat/bkv011. Epub 2015 Mar 3.

New designer drug alpha-pyrrolidinovalerophenone (PVP): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques.

J Mass Spectrom. 2009 Jun;44(6):952-64. doi: 10.1002/jms.1571.

[A new designer drug: methylone related death].

Orv Hetil. 2012 Feb 19;153(7):271-6. doi: 10.1556/OH.2012.29310.

Sudden death and resisted mechanical restraint: a case report.

J Am Geriatr Soc. 1993 Apr;41(4):424-5. doi: 10.1111/j.1532-5415.1993.tb06952.x.

Mechanisms of injury and death proximal to restraint use.

Arch Psychiatr Nurs. 2000 Dec;14(6):285-95. doi: 10.1053/apnu.2000.19091.

引用本文的文献

Acute pharmacological effects of α-PVP in humans: a naturalistic observational study.

Front Pharmacol. 2025 Jul 2;16:1626692. doi: 10.3389/fphar.2025.1626692. eCollection 2025.

Neuropsychopharmacology of Emerging Drugs of Abuse: - and -Halogen-Ring-Substituted α-PVP ("") Derivatives.

Int J Mol Sci. 2022 Feb 17;23(4):2226. doi: 10.3390/ijms23042226.

Toxicological Analysis of Intoxications with Synthetic Cathinones.

J Anal Toxicol. 2022 Aug 13;46(7):705-711. doi: 10.1093/jat/bkab102.

An updated review on synthetic cathinones.

Arch Toxicol. 2021 Sep;95(9):2895-2940. doi: 10.1007/s00204-021-03083-3. Epub 2021 Jun 8.

Pharmacokinetics of α-Pyrrolidinovalerophenone in Male Rats with and without Vaccination with an α-Pyrrolidinovalerophenone Vaccine.

J Pharm Pharm Sci. 2021;24:267-276. doi: 10.18433/jpps31832.

Flakka: New Dangerous Synthetic Cathinone on the Drug Scene.

Int J Mol Sci. 2020 Oct 31;21(21):8185. doi: 10.3390/ijms21218185.

Psychoactive Bath Salts and Neurotoxicity Risk.

Turk J Pharm Sci. 2020 Apr;17(2):235-241. doi: 10.4274/tjps.galenos.2018.40820. Epub 2020 Apr 24.

Designer drugs: mechanism of action and adverse effects.

Arch Toxicol. 2020 Apr;94(4):1085-1133. doi: 10.1007/s00204-020-02693-7. Epub 2020 Apr 6.

Fatal α-PVP and amphetamine poisoning during a sauna and autoerotic practices.

Forensic Sci Med Pathol. 2020 Sep;16(3):493-497. doi: 10.1007/s12024-020-00236-1. Epub 2020 Mar 26.

Clinical and toxicological findings of acute intoxication with synthetic cannabinoids and cathinones.

Acute Med Surg. 2015 Dec 28;3(3):230-236. doi: 10.1002/ams2.182. eCollection 2016 Jul.

Sudden death after sustained restraint following self-administration of the designer drug α-pyrrolidinovalerophenone.

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