Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark.
Trends Parasitol. 2014 Mar;30(3):136-40. doi: 10.1016/j.pt.2014.01.005. Epub 2014 Jan 31.
Recently, conflicting evidence has been published on the mode of transmission of the trichomonad Dientamoeba fragilis. Detection of D. fragilis DNA inside Enterobius vermicularis eggs agrees with the prediction of Dobell in 1940 that the eggs of a nematode act as a vector for transmission. However, the identification of a cyst stage of D. fragilis in the stool of rodents infected with a human isolate has also been reported, and this implies a life cycle similar to those of most other intestinal protistan parasites. Herein we discuss the recent data, identify gaps in the experimental evidence, and propose a method for determining which view of the life cycle of this organism is correct.
最近，有关纤毛滴虫脆弱双滴虫传播模式的证据相互矛盾。在人蛔虫卵内检测到脆弱双滴虫 DNA，这符合 1940 年多贝尔的预测，即线虫的卵充当传播媒介。然而，在感染人分离株的啮齿动物粪便中也发现了脆弱双滴虫的囊蚴阶段，这意味着它的生活史与大多数其他肠道原生动物寄生虫相似。本文讨论了最近的数据，确定了实验证据中的空白，并提出了一种方法来确定该生物体的生活史的哪种观点是正确的。
