Coleman Memorial Laboratory, UCSF Center for Integrative Neuroscience, University of California at San Francisco, San Francisco, CA 94143, USA.
Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Department of Otology and Laryngology, Harvard Medical School, Boston, MA 02114, USA.
Curr Opin Neurobiol. 2014 Feb;24(1):143-56. doi: 10.1016/j.conb.2013.11.009. Epub 2013 Dec 13.
Auditory cortical maps have been a long-standing focus of studies that assess the expression, mechanisms, and consequences of sensory plasticity. Here we discuss recent progress in understanding how auditory experience transforms spatially organized sound representations at higher levels of the central auditory pathways. New insights into the mechanisms underlying map changes have been achieved and more refined interpretations of various map plasticity effects and their consequences in terms of behavioral corollaries and learning as well as other cognitive aspects have been offered. The systematic organizational principles of cortical sound processing remain a key aspect in studying and interpreting the role of plasticity in hearing.
听觉皮层图谱一直是研究的重点,这些研究评估了感觉可塑性的表达、机制和后果。在这里,我们讨论了理解听觉经验如何在中枢听觉通路的较高水平上改变空间组织的声音表示的最新进展。我们对导致图谱变化的机制有了新的认识,并对各种图谱可塑性效应及其在行为后果、学习以及其他认知方面的影响提供了更精细的解释。皮质声音处理的系统组织原则仍然是研究和解释听力可塑性作用的关键方面。