Ullah Hameed, Samad Khalid, Khan Fauzia A
Department of Anaesthesiology, Aga Khan University Hospital, Stadium Road, PO Box 3500, Karachi, Pakistan, 74800.
Cochrane Database Syst Rev. 2014 Feb 4;2014(2):CD007080. doi: 10.1002/14651858.CD007080.pub2.
Postoperative pain may lead to adverse effects on the body, which might result in an increase in morbidity. Its management therefore poses a unique challenge for the clinician. Major shoulder surgery is associated with severe postoperative pain, and different modalities are available to manage such pain, including opioid and non-opioid analgesics, local anaesthetics infiltrated into and around the shoulder joint and regional anaesthesia. All of these techniques, alone or in combination, have been used to treat the postoperative pain of major shoulder surgery but with varying success.
The objective of this review was to compare the analgesic efficacy of continuous interscalene brachial plexus block (ISBPB) with parenteral opioid analgesia for pain relief after major shoulder surgery.
We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (2012, Issue 12), MEDLINE (1950 to December 2012), EMBASE (1980 to December 2012), Web of Science (1954 to December 2012), CINAHL (1982 to December 2012) and bibliographies of published studies.
We included randomized controlled trials assessing the effectiveness of continuous ISBPB compared with different forms of parenteral opioid analgesia in relieving pain in adult participants undergoing elective major shoulder surgery.
Two review authors independently assessed trial quality and extracted outcome data.
We included two randomized controlled trials (147 participants). A total of 17 participants were excluded from one trial because of complications related to continuous ISBPB (16) or parenteral opioid analgesia (one). Thus we have information on 130 participants (66 in the continuous ISBPB group and 64 in the parenteral opioid group). The studies were clinically heterogeneous. No meta-analysis was undertaken. However, results of the two included studies showed better pain relief with continuous ISBPB following major shoulder surgery and a lower incidence of complications when interscalene block is performed under ultrasound guidance rather than without it.
AUTHORS' CONCLUSIONS: Because of the small number of studies (two) relevant to the subject and the high risk of bias of the selected studies, no reasonable conclusion can be drawn.
术后疼痛可能会对身体产生不良影响,这可能导致发病率增加。因此,对其进行管理对临床医生构成了独特的挑战。肩部大手术会伴随严重的术后疼痛,有多种方式可用于管理此类疼痛,包括阿片类和非阿片类镇痛药、注入肩关节及其周围的局部麻醉药以及区域麻醉。所有这些技术单独或联合使用,都曾用于治疗肩部大手术的术后疼痛,但效果各异。
本综述的目的是比较连续肌间沟臂丛神经阻滞(ISBPB)与胃肠外阿片类镇痛在肩部大手术后缓解疼痛方面的镇痛效果。
我们检索了Cochrane对照试验中心注册库(CENTRAL)(2012年第12期)、MEDLINE(1950年至2012年12月)、EMBASE(1980年至2012年12月)、科学引文索引(1954年至2012年12月)、护理学与健康领域数据库(CINAHL)(1982年至2012年12月)以及已发表研究的参考文献。
我们纳入了评估连续肌间沟臂丛神经阻滞与不同形式胃肠外阿片类镇痛相比,在接受择期肩部大手术的成年参与者中缓解疼痛效果的随机对照试验。
两位综述作者独立评估试验质量并提取结果数据。
我们纳入了两项随机对照试验(147名参与者)。一项试验中共有17名参与者因与连续肌间沟臂丛神经阻滞相关的并发症(16例)或胃肠外阿片类镇痛相关的并发症(1例)而被排除。因此,我们有130名参与者的信息(连续肌间沟臂丛神经阻滞组66名,胃肠外阿片类组64名)。这些研究在临床方面存在异质性。未进行荟萃分析。然而,两项纳入研究的结果显示,肩部大手术后连续肌间沟臂丛神经阻滞的疼痛缓解效果更好,并且在超声引导下进行肌间沟阻滞时并发症发生率低于无超声引导时。
由于与该主题相关的研究数量较少(两项)且所选研究存在较高的偏倚风险,无法得出合理结论。