柯蒂氏器毛细胞中细胞被膜的区域特化

Regional specialization of the cell coat in the hair cells of the organ of Corti.

作者信息

Prieto J J, Merchan J A

机构信息

Department of Morphology, Faculty of Medicine, University of Alicante, Spain.

出版信息

Hear Res. 1987 Dec 31;31(3):223-7. doi: 10.1016/0378-5955(87)90191-2.

DOI:10.1016/0378-5955(87)90191-2

PMID:2449415

Abstract

The anionic sulfated groups of the cell coat glycoconjugates were studied in sensory and supporting cells of the organ of Corti with the colloidal iron hydroxide technique of Mowry, modified by Seno et al. [(1985) Histochemistry 82, 307-312]. This technique specifically stains the apical (endolymphatic) surface of both inner and outer hair cells. As this is the area at which the influx of potassium into the sensory cells takes place, the accumulation of negative charges in this location may be a mechanism to concentrate cations (mainly potassium) close to this portion of the hair cell membrane.

摘要

采用经Seno等人修改的Mowry氢氧化铁胶体技术（[(1985)组织化学82, 307 - 312]），对柯蒂氏器感觉细胞和支持细胞中细胞被糖结合物的阴离子硫酸基团进行了研究。该技术特异性地染色内、外毛细胞的顶端（内淋巴）表面。由于这是钾流入感觉细胞的区域，该位置负电荷的积累可能是一种将阳离子（主要是钾）聚集在毛细胞膜这一部分附近的机制。