[子宫内膜组织学诊断的不同方法比较研究]
[Different methods for the diagnosis of endometrial histological comparative study].
作者信息
Leng Xu, Wang Min, Zhang Shu-lan, Wang Dan, Cao Wei, Yang Xiang-hong
机构信息
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, China. Email:
出版信息
Zhonghua Fu Chan Ke Za Zhi. 2013 Dec;48(12):891-5.
OBJECTIVE
To evaluate the feasibility of endometrial sampler Pipelle for endometrial histologic diagnosis.
METHODS
Using prospective and self-control methods, 200 patients with endometrial biopsy firstly used Pipelle endometrial sampler for endometrial tissue, then followed by diagnostic curettage, the same pathologist evaluated the specimen quality and made the histologic diagnosis.
RESULTS
Totally 200 patients completed the observation, the specimen satisfaction of Pipelle was 93.0% (in this 200 cases, 186 cases were satisfactory), its pathological accuracy was 85.0% (in this 200 cases, 170 cases' pathological results are highly consistent with diagnostic curettage). There was no significant difference between two kinds of endometrial sampling (P > 0.05). There was no pain for patients during the Pipelle using process.
CONCLUSION
Pipelle could obtain satisfactory samples used for histological diagnosis in normal endometrium, simple hyperplasia, complex hyperplasia, atypical hyperplasia and endometrial cancer disease, because its pathological accuracy is so close to the diagnostic curettage, which may be used as a routine screening tool of endometrial diseases.
目的
评估子宫内膜取样器Pipelle用于子宫内膜组织学诊断的可行性。
方法
采用前瞻性自身对照方法，200例子宫内膜活检患者先用Pipelle子宫内膜取样器获取子宫内膜组织，随后进行诊断性刮宫，由同一位病理学家评估标本质量并做出组织学诊断。
结果
200例患者完成观察，Pipelle的标本满意度为93.0%（200例中186例满意），其病理准确率为85.0%（200例中170例病理结果与诊断性刮宫高度一致）。两种子宫内膜取样方法之间无显著差异（P>0.05）。患者在使用Pipelle过程中无疼痛。
结论
Pipelle在正常子宫内膜、单纯性增生、复杂性增生、不典型增生及子宫内膜癌疾病中均可获取用于组织学诊断的满意样本，因其病理准确率与诊断性刮宫相近，可作为子宫内膜疾病的常规筛查工具。
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