Liu H, Wang F-L, Zhao Y-M, Yao Y-Q, Li Y-L
a Department of Obstetrics and Gynecology , Chinese PLA General Hospital , Beijing , P. R. China.
b Department of Pathology , Chinese PLA General Hospital , Beijing , P. R. China.
J Obstet Gynaecol. 2015;35(5):508-11. doi: 10.3109/01443615.2014.970524.
The aim of this study is to investigate the accuracy and adequacy of the Pipelle endometrial sampler for endometrial biopsy as compared with those of conventional dilatation and curettage (D&C). A total of 245 patients subject to endometrial biopsy were included in this study. We have shown that the failure rates with D&C and Pipelle were 7.75% and 8.98%, respectively, without statistical difference. Additionally, the obtained specimen quality and accurate diagnosis of various diseases using the two methods had no significant statistical differences. Furthermore, patients experienced less pain when Pipelle sampler was used than D&C. Therefore, Pipelle sampler is effective in obtaining adequate endometrial tissue for histodiagnosis, and is applicable in most of the cases for Chinese endometrial biopsy.
本研究旨在探讨与传统刮宫术(D&C)相比,Pipelle子宫内膜取样器进行子宫内膜活检的准确性和充分性。本研究共纳入245例行子宫内膜活检的患者。我们发现,D&C和Pipelle的失败率分别为7.75%和8.98%,无统计学差异。此外,两种方法所获得的标本质量以及对各种疾病的准确诊断均无显著统计学差异。而且,使用Pipelle取样器时患者的疼痛程度低于D&C。因此,Pipelle取样器能有效地获取足够的子宫内膜组织用于组织学诊断,适用于大多数中国子宫内膜活检病例。