Ogun Oluwaseye Ayoola, Büki Bela, Cohn Edward S, Janky Kristen L, Lundberg Yunxia Wang
From the 1Boys Town National Research Hospital, Omaha, NE; and 2Department of Otolaryngology, County Hospital, Krems, Austria.
Menopause. 2014 Aug;21(8):886-9. doi: 10.1097/GME.0000000000000190.
This study was designed to examine the age and sex distribution and the effects of menopause in a large cohort of participants diagnosed with benign paroxysmal positional vertigo (BPPV).
We analyzed 1,377 BPPV patients and surveyed 935 women from this group-all diagnosed at the Boys Town National Research Hospital in the last decade.
A detailed age and sex distribution analysis of BPPV onset showed that aging had a profound impact on BPPV occurrence in both sexes, and that perimenopausal women were especially susceptible to BPPV (3.2:1 female-to-male ratio). The latter is a novel finding and was confirmed by a direct survey of female BPPV patients (168 participated). In addition, there was a pronounced female preponderance (6.8:1 female-to-male ratio) in BPPV in the teenage group despite its low prevalence in this age group.
Data suggest that hormonal fluctuations (especially during menopause) may increase the tendency to develop BPPV.
本研究旨在调查一大群被诊断为良性阵发性位置性眩晕（BPPV）的参与者的年龄和性别分布以及绝经的影响。
我们分析了1377例BPPV患者，并对该组中的935名女性进行了调查——所有患者均在过去十年内在博伊城国家研究医院被诊断。
对BPPV发病的详细年龄和性别分布分析表明，衰老对男女BPPV的发生都有深远影响，围绝经期女性尤其易患BPPV（女性与男性比例为3.2:1）。这是一个新发现，并通过对女性BPPV患者的直接调查（168人参与）得到了证实。此外，尽管青少年组BPPV患病率较低，但该组中女性明显占优势（女性与男性比例为6.8:1）。
数据表明，激素波动（尤其是在绝经期间）可能会增加发生BPPV的倾向。
