犬鼻黏膜和皮肤损伤处棘阿米巴分离株的特征分析
Characterization of isolates of Acanthamoeba from the nasal mucosa and cutaneous lesions of dogs.
作者信息
Carlesso A M, Mentz M B, da Machado M L S, Carvalho A, Nunes T E T, Maschio V J, Rott M B
机构信息
Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil,
出版信息
Curr Microbiol. 2014 Jun;68(6):702-7. doi: 10.1007/s00284-014-0532-9. Epub 2014 Feb 5.
Acanthamoeba spp. are free-living amoebae that are ubiquitously distributed in the environment and can cause encephalomyelitis in animals and humans. The factors that contribute to Acanthamoeba infections include parasite biology, genetic diversity, environmental spread, and host susceptibility. The aim of the present study was to characterize isolates of Acanthamoeba from the nasal mucosa and cutaneous lesions of dogs in order to access the occurence and pathogenicity of these organisms in this animal group. We studied 13 isolates of Acanthamoeba confirmed by polymerase chain reaction. They were sequenced, the genotype was determined, and their potential of pathogenicity was evaluated.
棘阿米巴属是自由生活的变形虫，广泛分布于环境中，可导致动物和人类发生脑脊髓炎。导致棘阿米巴感染的因素包括寄生虫生物学特性、遗传多样性、环境传播和宿主易感性。本研究的目的是对从犬鼻黏膜和皮肤病变中分离出的棘阿米巴进行特征分析，以了解这些微生物在该动物群体中的发生情况和致病性。我们研究了13株经聚合酶链反应确认的棘阿米巴分离株。对它们进行了测序，确定了基因型，并评估了它们的致病潜力。
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