Departamento de Microbiologia, Imunologia e Parasitogia, Instituto de Ciências Básicas da Saúde, Setor de Parasitologia, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite 500, Porto Alegre, RS, Brazil.
Acta Trop. 2011 Mar;117(3):233-5. doi: 10.1016/j.actatropica.2010.12.008. Epub 2010 Dec 30.
Species of Acanthamoeba, known to cause keratitis (AK) and granulomatous encephalitis in humans are frequently isolated from a variety of water sources. In this study, 13 Acanthamoeba isolates from swimming pools were classified at the genotype level based on the sequence analysis of the Acanthamoeba small-subunit rRNA gene. Nine of the 13 isolates were genotype T5, three were genotype T4, and one was T3. Several genotypes have been reported worldwide as causative agents of AK, including genotypes T3, T4, and T5. The present study indicates that genotype T5 is a common contaminant in swimming-pool water.
棘阿米巴属的一些种,已知可引起人类角膜炎(AK)和肉芽肿性脑炎,常从各种水源中分离出来。在这项研究中,根据棘阿米巴小亚基 rRNA 基因的序列分析,对来自游泳池的 13 株棘阿米巴进行了基因型分类。13 株分离株中有 9 株为 T5 基因型,3 株为 T4 基因型,1 株为 T3 基因型。有几种基因型已被报道为 AK 的病原体,包括基因型 T3、T4 和 T5。本研究表明 T5 基因型是游泳池水中的一种常见污染物。