Department of Radiology, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon 420-767, Korea.
Department of Pathology, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon 420-767, Korea.
Korean J Radiol. 2014 Jan-Feb;15(1):12-9. doi: 10.3348/kjr.2014.15.1.12. Epub 2014 Jan 8.
To evaluate the retrieval rate and accuracy of ultrasound (US)-guided 14-G semi-automated core needle biopsy (CNB) for microcalcifications in the breast.
US-guided 14-G semi-automated CNB procedures and specimen radiography were performed for 33 cases of suspicious microcalcifications apparent on sonography. The accuracy of 14-G semi-automated CNB and radiology-pathology concordance were analyzed and the microcalcification characteristics between groups with successful and failed retrieval were compared.
Thirty lesions were successfully retrieved and the microcalcification retrieval rate was 90.9% (30/33). Thirty lesions were successfully retrieved. Twenty five were finally diagnosed as malignant (10 invasive ductal carcinoma, 15 ductal carcinoma in situ [DCIS]) and five as benign. After surgery and mammographic follow-up, the 25 malignant lesions comprised 12 invasive ductal carcinoma and 13 DCIS. Three lesions in the failed retrieval group (one DCIS and two benign) were finally diagnosed as two DCIS and one benign after surgery. The accuracy of 14-G semi-automated CNB was 90.9% (30/33) because of two DCIS underestimates and one false-negative diagnosis. The discordance rate was significantly higher in the failed retrieval group than in the successful retrieval group (66.7% vs. 6.7%; p < 0.05). Punctate calcifications were significantly more common in the failed retrieval group than in the successful retrieval group (66.7% vs. 3.7%; p < 0.05).
US-guided 14-G semi-automated CNB could be a useful procedure for suspicious microcalcifications in the breast those are apparent on sonography.
评估超声引导下 14G 半自动核心针活检（CNB）对乳腺微钙化的检出率和准确率。
对 33 例超声显示可疑微钙化的患者进行了超声引导下 14G 半自动 CNB 操作和标本 X 线摄影。分析了 14G 半自动 CNB 的准确率和影像学-病理学的一致性，并比较了成功和失败取检组的微钙化特征。
30 个病灶成功取检，微钙化取检率为 90.9%（30/33）。30 个病灶成功取检。25 个最终诊断为恶性（10 个浸润性导管癌，15 个导管原位癌），5 个为良性。手术后和乳腺 X 线摄影随访显示，25 个恶性病变包括 12 个浸润性导管癌和 13 个导管原位癌。失败取检组的 3 个病灶（1 个导管原位癌和 2 个良性）在手术后最终诊断为 2 个导管原位癌和 1 个良性。由于 2 个导管原位癌低估和 1 个假阴性诊断，14G 半自动 CNB 的准确率为 90.9%（30/33）。失败取检组的不一致率明显高于成功取检组（66.7%比 6.7%；p<0.05）。点状钙化在失败取检组明显更常见（66.7%比 3.7%；p<0.05）。
超声引导下 14G 半自动 CNB 对超声显示的乳腺可疑微钙化是一种有用的方法。
