Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
PLoS One. 2014 Jan 31;9(1):e87396. doi: 10.1371/journal.pone.0087396. eCollection 2014.
Chronic abdominal pain is one of the most common chief complaints, but the underlying pathophysiology often remains unknown after routine clinical evaluation. Capsule endoscopy (CE) is a new technique for the visualization of the entire small bowel. The aim of this study was to evaluate the diagnostic efficacy of CE in patients with chronic abdominal pain of obscure origin.
Two hundred forty three patients with chronic abdominal pain with no significant lesions were enrolled in this study. CE was performed in all patients.
A diagnosis was made in 23.0% of patients screened with CE. Of the 243 patients, 19 (7.8%) were diagnosed with Crohn's disease, 15 (6.2%) with enteritis, 11 (4.5%) with idiopathic intestinal lymphangiectasia, 5 (2.1%) with uncinariasis, and a number of other diagnoses including small bowel tumor, ascariasis, and anaphylactoid purpura. Five patients had abnormal transit time, and capsule retention occurred in two patients.
In contrast to other previous studies, we found that CE is an effective diagnostic tool for patients with abdominal pain.
慢性腹痛是最常见的主诉之一，但在常规临床评估后，其潜在的病理生理学通常仍不清楚。胶囊内镜（CE）是一种用于观察整个小肠的新技术。本研究旨在评估 CE 在不明原因慢性腹痛患者中的诊断效果。
本研究纳入了 243 例慢性腹痛且无明显病变的患者。所有患者均行 CE 检查。
CE 筛查出的患者中有 23.0%得到明确诊断。243 例患者中，19 例（7.8%）诊断为克罗恩病，15 例（6.2%）为肠炎，11 例（4.5%）为特发性肠淋巴管扩张症，5 例（2.1%）为鞭虫病，还有一些其他诊断，包括小肠肿瘤、蛔虫病和过敏性紫癜。5 例患者存在异常转运时间，2 例患者出现胶囊滞留。
与其他先前的研究不同，我们发现 CE 是腹痛患者的一种有效诊断工具。
